Skip to content
My WebMD Sign In, Sign Up

Botox Cosmetic intramuscular

General Anesthetics (Inhl)/Neuromuscular Blocking Agents

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

When these two medicines are taken together, the effects of the muscle relaxant may increase.

What might happen:

The intentional blocking of transmission to nerve and muscle by the muscle relaxant medicine may be increased or prolonged.

What you should do about this interaction:

These medicines are used during surgical procedures or in a hospital. If you are to have either inpatient or outpatient surgery, or are to be admitted to the hospital, make sure that all the healthcare professionals are aware of all the different medicines that you are taking. This includes prescription medicines, herbal drugs, and nutraceuticals.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.


1.Miller RD, Eger EI 2nd, Way WL, Stevens WC, Dolan WM. Comparative neuromuscular effects of Forane and halothane alone and in combination with d-tubocurarine in man. Anesthesiology 1971 Jul;35(1):38-42.
2.Miller RD, Way WL, Dolan WM, Stevens WC, Eger EI 2nd. Comparative neuromuscular effects of pancuronium, gallamine, and succinylcholine during forane and halothane anesthesia in man. Anesthesiology 1971 Nov; 35(5):509-14.
3.Miller RD, Way WL, Dolan WM, Stevens WC, Eger EI 2nd. The dependence of pancuronium- and d-tubocurarine-induced neuromuscular blockades on alveolar concentrations of halothane and forane. Anesthesiology 1972 Dec; 37(6):573-81.
4.Fogdall RP, Miller RD. Neuromuscular effects of enflurane, alone and combined with d- Tubocurarine, pancuronium, and succinylcholine, in man. Anesthesiology 1975 Feb;42(2):173-8.
5.Vitez TS. Potency of metocurine during halothane-N2O and N2O-narcotic anesthesia. Anesth Analg 1978 Jan-Feb;57(1):116-7.
6.Sebel PS, Bovill JG, Wauquier A, Rog P. Effects of high-dose fentanyl anesthesia on the electroencephalogram. Anesthesiology 1981 Sep; 55(3):203-11.
7.Artru AA, Nugent M, Michenfelder JD. Enflurane causes a prolonged and reversible increase in the rate of CSF production in the dog. Anesthesiology 1982 Oct;57(4):255-60.
8.Stirt JA, Katz RL, Murray AL, Schehl DL, Lee C. Modification of atracurium blockade by halothane and by suxamethonium. A review of clinical experience. Br J Anaesth 1983;55 Suppl 1:71S-75S.
9.Brandom BW, Cook DR, Woelfel SK, Rudd GD, Fehr B, Lineberry CG. Atracurium infusion requirements in children during halothane, isoflurane, and narcotic anesthesia. Anesth Analg 1985 May;64(5):471-6.
10.Rupp SM, Miller RD, Gencarelli PJ. Vecuronium-induced neuromuscular blockade during enflurane, isoflurane, and halothane anesthesia in humans. Anesthesiology 1984 Feb;60(2):102-5.
11.Ostergaard D, Engbaek J, Viby-Mogensen J. Adverse reactions and interactions of the neuromuscular blocking drugs. Med Toxicol Adverse Drug Exp 1989 Sep-Oct;4(5):351-68.
12.Swen J, Rashkovsky OM, Ket JM, Koot HW, Hermans J, Agoston S. Interaction between nondepolarizing neuromuscular blocking agents and inhalational anesthetics. Anesth Analg 1989 Dec;69(6):752-5.
13.Withington DE, Donati F, Bevan DR, Varin F. Potentiation of atracurium neuromuscular blockade by enflurane: time- course of effect. Anesth Analg 1991 Apr;72(4):469-73.

See 23 Reviews for this Drug. - OR -

Review this Treatment

Find a Drug:

by name or medical condition or shape/color (Pill Identifier)

(for example: aspirin)

(for example: diabetes)

Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Ask the pharmacist

Questions about medications? Get expert answers by video or live chat about allergies, pregnancy, sleep, and more.
See the Ask the Pharmacist event schedule.

Ask a Question

Popular Slideshows & Tools on WebMD

hands on abdomen
Can you catch one?
Woman sitting in front of UV lights
Is yours working?
woman using breath spray
What's causing yours?
womans hand on abdomen
Are you ready for baby?
MS Overview
Recognizing symptoms.
bowl of yogurt with heart shape
Eat for a healthy heart.
woman doing pushups
To help you get fit.
Colored x-ray of tooth decay
Know what to look for.
Woman sitting with child
Do you know the symptoms?
Stings, bites, burns, and more.
Allentown, PA
Are you living in one?
Thyroid exam
See how much you know.

Women's Health Newsletter

Find out what women really need.

WebMD the app

Get trusted health information. Whenever. Wherever... with your iPhone, iPad or Android.

Find Out More

IMPORTANT: About This Section and Other User-Generated Content on WebMD

The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Some of these opinions may contain information about treatment or uses of drug products that have not been approved by the U.S. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment.

Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately.