Telaprevir/Selected CYP 3A4-PgP Inducers
How the interaction occurs:
Rifampin and St. John's wort may speed up how quickly your liver processes telaprevir.
What might happen:
The amount of telaprevir in your blood may decrease and it may not work as well.
What you should do about this interaction:
Make sure your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together or if you have taken rifampin or St. John's wort in the previous two weeks, or if you stop taking St. John's wort. Your doctor may want to adjust your medicines.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.Reference:1.Incivek (telaprevir) US prescribing information. Vertex Pharmaceuticals Incorporated April, 2013.