Skip to content
My WebMD Sign In, Sign Up

Aminosyn 10 % intravenous

Selected Sympathomimetics/Linezolid; Rasagiline; Selegiline

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

When these two medicines are taken together, your body may not process sympathomimetics properly.

What might happen:

You may experience increased blood pressure, rapid heartbeat, seizures, or hallucinations.

What you should do about this interaction:

Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these two medicines together. They may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

References:

1.Goldberg LI. Monoamine oxidase inhibitors. Adverse reactions and possible mechanisms. JAMA 1964 Nov 2;190(5):456-62.
2.Pettinger WA, Soyangco FG, Oates JA. Inhibition of monoamine oxidase in man by furazolidone. Clin Pharmacol Ther 1968 Jul-Aug;9(4):442-7.
3.Adderall XR (amphetamine) US prescribing information. Shire US Inc. December, 2013.
4.Ritalin LA (methylphenidate hydrochloride) US prescribing information. Novartis Pharmaceuticals Corporation December, 2013.
5.Focalin (dexmethylphenidate hydrochloride) US prescribing information. Novartis Pharmaceuticals Corporation December, 2013.
6.Parnate (tranylcypromine sulfate) US prescribing information. GlaxoSmithKline May, 2010.
7.Cuthbert MF, Greenberg MP, Morley SW. Cough and cold remedies: a potential danger to patients on monoamine oxidase inhibitors. Br Med J 1969 Feb 15; 1(5641):404-6.
8.Smookler S, Bermudez AJ. Hypertensive crisis resulting from an MAO inhibitor and an over-the-counter appetite suppressant. Ann Emerg Med 1982 Sep;11(9):482-4U.
9.Mason AM, Buckle RM. "Cold" cures and monoamine-oxidase inhibitors. Br Med J 1969 Mar 29;1(5647):845-6.
10.LLOYD JT, WALKER DR. DEATH AFTER COMBINED DEXAMPHETAMINE AND PHENELZINE. Br Med J 1965 Jul 17;2(5454):168-9.
11.Krisko I, Lewis E, Johnson JE 3rd. Severe hyperpyrexia due to tranylcypromine-amphetamine toxicity. Ann Intern Med 1969 Mar; 70(3):559-64.
12.Boakes AJ, Laurence DR, Teoh PC, Barar FS, Benedikter LT, Prichard BN. Interactions between sympathomimetic amines and antidepressant agents in man. Br Med J 1973 Feb 10;1(5849):311-5.
13.Elis J, Laurence DR, Mattie H, Prichard BN. Modification by monoamine oxidase inhibitors of the effect of some sympathomimetics on blood pressure. Br Med J 1967 Apr 8;2(5544):75-8.
14.HORWITZ D, GOLDBERG LI, SJOERDSMA A. Increased blood pressure responses to dopamine and norepinephrine produced by monoamine oxidase inhibitors in man. J Lab Clin Med 1960 Nov;56:747-53.
15.Cuthbert MF, Vere DW. Potentiation of the cardiovascular effects of some catecholamines by a monoamine oxidase inhibitor. Br J Pharmacol 1971 Oct; 43(2):471P-472P.
16.Hornykiewicz O. Dopamine (3-hydroxytyramine) and brain function. Pharmacol Rev 1966 Jun;18(2):925-64.
17.GOLDBERG LI. MONOAMINE OXIDASE INHIBITORS. ADVERSE REACTIONS AND POSSIBLE MECHANISMS. JAMA 1964 Nov 2;190:456-62.
18.Kopin IJ. Biochemical aspects of release of norepinephrine and other amines from sympathetic nerve endings. Pharmacol Rev 1966 Mar; 18(1):513-23.
19.BETHUNE HC, BURRELL RH, CULPAN RH, OGG GJ. VASCULAR CRISES ASSOCIATED WITH MONOAMINE-OXIDASE INHIBITORS. Am J Psychiatry 1964 Sep;121:245-8.
20.O'Dea K, Rand MJ. Interaction between amphetamine and monoamine oxidase inhibitors. Eur J Pharmacol 1969 May;6(2):115-20.
21.Eldepryl (selegiline) US prescribing information. Somerset Pharmaceuticals February, 1997.
22.Emsam (selegline) US prescribing information. Somerset February, 2008.
23.Azilect (rasagiline) US prescribing information. Teva Neurosciences Inc. December, 2009.
24.Zyvox (linezolid) US prescribing information. Pfizer January, 2014.

Be the first to share your experience with this drug.

Review this Treatment

Find a Drug:

by name or medical condition or shape/color (Pill Identifier)

(for example: aspirin)

(for example: diabetes)

Report Problems to the Food and Drug Administration
 
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Ask the pharmacist

Questions about medications? Get expert answers by video or live chat about allergies, pregnancy, sleep, and more.
See the Ask the Pharmacist event schedule.

Ask a Question

Popular Slideshows & Tools on WebMD

hands on abdomen
Can you catch one?
Woman sitting in front of UV lights
Is yours working?
woman using breath spray
What's causing yours?
womans hand on abdomen
Are you ready for baby?
MS Overview
Recognizing symptoms.
bowl of yogurt with heart shape
Eat for a healthy heart.
woman doing pushups
To help you get fit.
Colored x-ray of tooth decay
Know what to look for.
Woman sitting with child
Do you know the symptoms?
mosquito
Stings, bites, burns, and more.
Allentown, PA
Are you living in one?
Thyroid exam
See how much you know.

Women's Health Newsletter

Find out what women really need.

WebMD the app

Get trusted health information. Whenever. Wherever... with your iPhone, iPad or Android.

Find Out More

IMPORTANT: About This Section and Other User-Generated Content on WebMD

The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Some of these opinions may contain information about treatment or uses of drug products that have not been approved by the U.S. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment.

Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately.