Hydralazine/Food Interaction
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug, changing your diet or commencing any course of treatment.
Medical warning:
Very important. A change in your diet, medicine, or dosage may be necessary. Promptly consult your doctor or pharmacist.
How the interaction occurs:
The cause of the interaction is not known.
What might happen:
Your blood levels of hydralazine may decrease. Also, the beneficial blood pressure lowering effect may decrease.
What you should do about this interaction:
Always take this medicine with meals or always take it on an empty stomach (one hour before or two hours after food). Tell your healthcare professional (e.g., doctor or pharmacist) immediately if you develop headaches. Contact your healthcare professional for more information.Your healthcare professionals may be aware of this interaction and may be monitoring you for it. Do not start, stop, or change your medicine or diet before checking with them first.
References:
1.Melander A, Danielson K, Hanson A, Rudell B, Schersten B, Thulin T, Wahlin E. Enhancement of hydralazine bioavailability by food. Clin Pharmacol Ther 1977 Jul;22(1):104-7.
2.Shepherd AM, Irvine NA, Ludden TM. Effect of food on blood hydralazine levels and response in hypertension. Clin Pharmacol Ther 1984 Jul; 36(1):14-8.
