Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
What might happen:
Using these medicines together may cause your blood pressure to become very low and you may lose consciousness.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know right away that you are taking these medicines together. Let your doctor know if you have any dizziness, lightheadedness, or loss of consciousness.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
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2.USFood and Drug Administration. FDA Drug Safety Communication: Abnormal heart rhythms associated with use of Anzemet (dolasetron mesylate). Available at: http://www.fda.gov/Drugs/DrugSafety/ucm237081.htm December 17, 2010.
3.Zofran (ondansetron) US prescribing information. GlaxoSmithKline December, 2013.
4.Bowron A. Practical considerations in the use of apomorphine injectable. Neurology 2004 Mar 23;62(6 Suppl 4):S32-6.