Skip to content

    Read user comments about the side effects, benefits, and effectiveness of Benadryl Spray topical.

    Overall User Ratings

    8 Total User Reviews

    User Reviews

    1-5 of 8 Next»
    Condition: Other
    10/3/2013 5:06:56 PM

    Reviewer: nobohobo, 35-44 Female on Treatment for 1 to 6 months (Patient)

    Effectiveness

    Current Rating: 5

    Ease of Use

    Current Rating: 4

    Satisfaction

    Current Rating: 3

    Comment:
    Works very well topically with insect bites, but after using for a couple of days I noticed a pattern of extreme fatigue about an hour after use... the bottle says to NEVER combine with oral dosage, which leads me to believe that it is absorbed through the skin to give same side effects. Will use sparingly as I can't nap all the time!

    Condition: Other
    7/29/2011 11:46:02 AM

    Reviewer: Toytrain, 55-64 Female on Treatment for less than 1 month (Patient)

    Effectiveness

    Current Rating: 4

    Ease of Use

    Current Rating: 3

    Satisfaction

    Current Rating: 3

    Comment:
    When spraying on myself, I cannot always hold the bottle upright, and when I spray while holding the bottle sideways, the medicine leaks onto my hand (and wastes the medicine) otherwise the spray is effective in healing bug bites after a few days. I had previously used the stick version, but I can no longer find it in the stores. I realize I can probably order it online, but who wants to wait fo ... Show Full Comment

    Condition: Other
    6/9/2011 12:12:16 AM

    Reviewer: bajaDean, 45-54 Male on Treatment for 2 to less than 5 years (Patient)

    Effectiveness

    Current Rating: 5

    Ease of Use

    Current Rating: 5

    Satisfaction

    Current Rating: 5

    Comment:
    I purchased it for bee sting allergic reactions in hopes I would not have to take the oral pills which knock me out. and it works great... I can spray locally and i am just fine it stops me from going into serious stages. Next i have allergic reactions to jellyfish and man-o-wars. and my former treatment was to take the oral and get knocked out for 8 hours. So I decided to try th ... Show Full Comment

    Condition: Other
    7/29/2010 2:45:19 AM

    Reviewer: 45-54 Female on Treatment for less than 1 month (Patient)

    Effectiveness

    Current Rating: 5

    Ease of Use

    Current Rating: 5

    Satisfaction

    Current Rating: 5

    Comment:
    great for prickly heat and bites.

    Condition: Other
    7/2/2009 3:36:27 PM

    Reviewer: 35-44 Male on Treatment for less than 1 month (Patient)

    Effectiveness

    Current Rating: 4

    Ease of Use

    Current Rating: 5

    Satisfaction

    Current Rating: 4

    Comment:
    I applied Benadryl Spray to my poison ivy rash and it does an excellent job of easing the itching for hours at a time. The only way it could be more effective is if it lasted longer or eliminated the rash entirely.

    1-5 of 8 Next»

    Ask the pharmacist

    Questions about medications? Get expert answers by video or live chat about allergies, pregnancy, sleep, and more.
    See the Ask the Pharmacist event schedule.

    Ask a Question

    Popular Slideshows & Tools on WebMD

    disciplining a boy
    Types, symptoms, causes.
    fruit drinks
    Eat these to think better.
    embarrassed woman
    Do you feel guilty after eating?
    diabetes supply kit
    Pack and prepare.
    handful of vegetables and vitamins
    Diet tips and mistakes.
    birth control pills
    Which kind is right for you?
    Remember your finger
    Are you getting more forgetful?
    sticky notes on face
    10 tips to clear your brain fog.
    Close up of eye
    12 reasons you're distracted.
    Trainer demonstrating exercise for RA
    Exercises for your joints.
    apple slices with peanut butter
    What goes best with workouts?
    woman having a good day
    Revitalize your life.

    Newsletters

    Subscribe to free WebMD newsletters.

    • WebMD Daily

      WebMD Daily

      Subscribe to the WebMD Daily, and you'll get today's top health news and trending topics, and the latest and best information from WebMD.

    • Men's Health

      Men's Health

      Subscribe to the Men's Health newsletter for the latest on disease prevention, fitness, sex, nutrition, and more from WebMD.

    • Women's Health

      Women's Health

      Subscribe to the Women's Health newsletter for the latest on disease prevention, fitness, sex, diet, anti-aging, and more from WebMD.

    By clicking Submit, I agree to the WebMD Terms & Conditions & Privacy Policy and understand that I may opt out of WebMD subscriptions at any time.

    WebMD the app

    Get trusted health information. Whenever. Wherever... with your iPhone, iPad or Android.

    Find Out More
    IMPORTANT: About This Section and Other User-Generated Content on WebMD

    The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Some of these opinions may contain information about treatment or uses of drug products that have not been approved by the U.S. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment.

    Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately.