Show ratings & reviews for

3.5 Overall Rating

Effectiveness

Ease of Use

Satisfaction

Most voted positive review

18 People found this comment helpful

My left leg has 100 % blockage an right has 70 %. My pain level was 8 to 9. Oxycodone was being used + Tylonal etc, heavy doses. After 6 weeks the pain went away using pentoxiflline. I have been pain free for two months, hopefully this will continue.

Shared reviews and ratings

DB | 75 or over | Male | On medication for 1 to 6 months | Patient
3/13/2024
Condition: Peripheral Vascular Disease
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction

flatulent, but improving water retention a bit anxious can walk further distances but at a slightly lower pace have been using 10 weeks

Report this postFill 3Created with Sketch.
KBB | 55-64 | Female | On medication for 1 to 6 months | Patient
12/2/2023
Condition: Other
Overall rating 4.7
Effectiveness
Ease of Use
Satisfaction

Taking for radiation fibrosis of right chest, post mastectomy and radiation therapy for breast cancer. Have taken for 4 weeks so far, 400mg twice a day, and seems to be helping the tightness and pain.

Report this postFill 3Created with Sketch.
Kimberly | 55-64 | Female | On medication for 6 months to less than 1 year | Patient
8/21/2023
Condition: Other
Overall rating 4.3
Effectiveness
Ease of Use
Satisfaction

Please comment if you have had a similar experience. After chemo and radiation, I was diagnosed with peripheral neuropathy, and no medication assisted with the pain in both of my legs. I began taking Pentoxifylline for a different purpose and my pain stopped almost completely! I was looking for relief for over a year and this was the only thing that actually worked for my pain. A vascular surgeon told me that I do not have Peripheral Arterie Disease and he was not sure why it worked. My general doctor agreed to prescribe it for me. Recently I noticed a little pain so I increased the medication from two pills to three pills a day which has helped. I do however feel a little more tired and "dizzied" or "foggy" for some reason though. Overall it is definitely worth it because I do not have the terrible pain that I had been dealing with for so long. Read More Read Less

Report this postFill 3Created with Sketch.
Darlene | 55-64 | Female | On medication for 2 to less than 5 years | Patient
2/1/2023
Condition: Peripheral Vascular Disease
Overall rating 4.3
Effectiveness
Ease of Use
Satisfaction

I was prescribed for this medication for low blood flow to my legs. Experienced excruciating pain in leg. Have been on it for two years. However I recently started getting severe cramps in my leg. When I taking it for a month, the cramps went away. Started back taking it and leg cramps returned.

Report this postFill 3Created with Sketch.
Robin | 55-64 | Female | On medication for less than 1 month | Patient
1/19/2023
Condition: Other
Overall rating 3.0
Effectiveness
Ease of Use
Satisfaction

I did not give higher ratings as just started it. Prescribed for radiation necrosis of the mouth, gums due to radiation to head and neck severely damaged all my once perfect beautiful straight white teeth ?? No dentist or oral surgeon wanted to touch me as I have 12 exposed nerves had 3 emergency extractions 1 month and 1 week ago that within 18 hours were dry sockets. They still are not healing well and have exposed bone. The rads oncologist at Moffitt in Tampa doesn’t believe the effectiveness of hyperbaric oxygen treatments which oral surgeon and dentist say I require but still will not do any extractions regardless so this is the only thing moffitt would prescribe. Anyone else get prescribed this drug for the same reason? Read More Read Less

Report this postFill 3Created with Sketch.
kats | 65-74 | Female | On medication for 1 to 6 months | Patient
4/3/2022
Condition: Other
Overall rating 2.3
Effectiveness
Ease of Use
Satisfaction

I am using this med after 29 radiation treatments for endometrial cancer. I have experienced constant diarrea, and burning in vaginal area. Also bloating and gas discomfort.

Report this postFill 3Created with Sketch.
michael shumaker | 45-54 | On medication for less than 1 month | Patient
1/19/2019
Condition: Leg Pain when Walking; Absent at Rest
Overall rating 3.7
Effectiveness
Ease of Use
Satisfaction

So far I have been dizzy and very nauseous the first 30 min of taking the medication.However I have noticed less aching and pain in my legs so I will continue to take this medication I hope I adjust to it the longer I take it

Report this postFill 3Created with Sketch.
dang | 65-74 | On medication for 1 to less than 2 years | Patient
4/16/2018
Condition: Peripheral Vascular Disease
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction

Noted that I have had an increase in body hair since taking this drug. On my arms, legs and chest. Has anyone else experienced this??

Report this postFill 3Created with Sketch.
DonPaul | 65-74 | Male | On medication for 1 to less than 2 years | Patient
3/7/2018
Condition: Other
Overall rating 4.7
Effectiveness
Ease of Use
Satisfaction

What good is writing a review like the one reviewer ask what is longest time period you can continue to take the medication and no... is not a good answer for as long as your doctor prescribes it. How long? 1 year, 2 years, the rest of your life. how about an answer.

Report this postFill 3Created with Sketch.
Spotty1235 | 65-74 | Female | On medication for less than 1 month | Patient
6/1/2017
Condition: Other
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

Given for loss of taste and smell. Have been only taking 17 days but have had improvement and expect much more,

Report this postFill 3Created with Sketch.
DOCJAY | 65-74 | Male | On medication for less than 1 month | Patient
9/2/2016
Condition: Peripheral Vascular Disease
Overall rating 2.3
Effectiveness
Ease of Use
Satisfaction

just finished first month,too soon to tell its not like zantac where you have heartburn and you take it and it works in 30min. it takes time for trental to buildup in the tissues.will have to give it more time a couple of more months.wanted to try pletal,but will wait and give this a chance.

Report this postFill 3Created with Sketch.
Anonymous | 55-64 | Male | On medication for 1 to less than 2 years | Patient
4/24/2016
Condition: Leg Pain when Walking; Absent at Rest
Overall rating 3.3
Effectiveness
Ease of Use
Satisfaction

Minor improvement, still get pain in my legs but it is less ,I am also taking Cordarone which apparently interacts with it. So will discuss with DR.

Report this postFill 3Created with Sketch.
Tedgatz | 75 or over | Male | On medication for 6 months to less than 1 year | Patient
7/27/2014
Condition: Peripheral Vascular Disease
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

I had the worst pain of my life, with 100% artery blockage in my left leg, and 70% in my right leg. My old Doctor friend prescribed pentoxiflline, said it would take several weeks to take effect, and it began working, and I haven't had any pain since. I take two 400's in the morning and two at bedtime. My question is, how long can I take this medication. I started taking these about 10 mo's ago. I have no side effects and can play golf 3 times per week, I am 88 and shoot my age. Thanks, Ted G

Report this postFill 3Created with Sketch.
Anonymous | 65-74 | Male | On medication for 1 to less than 2 years | Patient
3/13/2014
Condition: Peripheral Vascular Disease
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction
Report this postFill 3Created with Sketch.
missmaplefealf | 35-44 | Female | On medication for less than 1 month | Patient
2/2/2014
Condition: Peripheral Vascular Disease
Overall rating 3.3
Effectiveness
Ease of Use
Satisfaction

Side effects were massive: vomiting, headache and hypotension. The blood circulation effect worked, but afraid of those other effects!

Report this postFill 3Created with Sketch.
T. G. | 75 or over | Male | On medication for 1 to 6 months | Patient
1/26/2014
Condition: Peripheral Vascular Disease
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

My left leg has 100 % blockage an right has 70 %. My pain level was 8 to 9. Oxycodone was being used + Tylonal etc, heavy doses. After 6 weeks the pain went away using pentoxiflline. I have been pain free for two months, hopefully this will continue.

Report this postFill 3Created with Sketch.
Anonymous | 65-74 | Female | Patient
10/28/2013
Condition: Peripheral Vascular Disease
Overall rating 3.3
Effectiveness
Ease of Use
Satisfaction

I been on Pentoxifylline for nearly 4 yrs. it worked terrific for the first year then I noticed I was getting slight cramps in knees and legs. I passed if off to old age but this gradually got worse. The leg pain increased and the MD upped dosage to 6/day. The legs/knee cramps continued to get worse and I developed a blood clot-that may be unrelated or not. Much PT and Vit C therapy helped the knee/leg issue but finally, the legs felt like matchsticks when I got out of bed - no control or power. When I stopped the Pentoxifhylline and went on coumadin -OMG the next day I felt I could walk a mile. It is possible that Pentoxiphylline has a max use time. Vit C therapy helped get the muscles out of tightning/knotting up. But, I sure went thru a painful month trying to resolve the leg muscle issue. Pay attention to any leg or knee tightning you feel. It is not old age it is from the pentoxiphyllin. You may need to go off it a while then go back. Read More Read Less

Report this postFill 3Created with Sketch.
BobGay | 65-74 | Male | On medication for 1 to 6 months | Patient
8/8/2013
Condition: Peripheral Vascular Disease
Overall rating 4.7
Effectiveness
Ease of Use
Satisfaction

I've been on it for 3 months and my walking has increased about 25%. I measure that by the distance between stops. I hope in time it will increase even more.

Report this postFill 3Created with Sketch.
krazy01 | 35-44 | Male | On medication for 6 months to less than 1 year | Patient
5/1/2013
Condition: Other
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction

poor blood on legs

Report this postFill 3Created with Sketch.
Greg | 45-54 | Male | On medication for 6 months to less than 1 year | Patient
1/22/2013
Condition: Other
Overall rating 3.3
Effectiveness
Ease of Use
Satisfaction

I am taking for Pyronie's disease but have hives, blisters and severe itching all up my arms and skull.

Report this postFill 3Created with Sketch.

IMPORTANT INFORMATION ABOUT USER-GENERATED CONTENT ON WEBMD

The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions.

Read More