Reviewer: mcjudy, 55-64 Female on Treatment for 10 years or more (Patient)

Comment:
In the ER, this drug was given to me IV. Horrible experience. I started getting 'antsy' then sort of nervous but the worst thing--I felt like I was going to jump out of my skin. It's hard to describe but I felt like I had been given a massive dose of CAFFINE..

Comment:
In the ER, this drug was given to me IV. Horrible experience. I started getting 'antsy' then sort of nervous but the worst thing--I felt like I was going to jump out of my skin. It's hard to describe but I felt like I had been given a massive dose of CAFFINE..
Hide Full Comment

Reviewer: juli, 45-54 Female on Treatment for 10 years or more (Patient)

Comment:
Been using DHE45 injections subcutaneously since 1993 (today is Aug. 1, 2009) almost daily, with unfortunate chronic daily migraine/head pain/nausea/vomiting. This drug helps to reduce the pain level most of the time to a level '5', my usual daily pain level. It does burn when injecting, but one can tolerate that for the few seconds it takes to inject. Nothing prevents my migraines, so we have ... Show Full Comment

Comment:
Been using DHE45 injections subcutaneously since 1993 (today is Aug. 1, 2009) almost daily, with unfortunate chronic daily migraine/head pain/nausea/vomiting. This drug helps to reduce the pain level most of the time to a level '5', my usual daily pain level. It does burn when injecting, but one can tolerate that for the few seconds it takes to inject. Nothing prevents my migraines, so we have to 'treat' them with vascular constrictors. Pain meds do not help. This drug has been one of two (the other being Relpax pills) that are my 'drug of choice' to help treat this pain daily. I have NO IDEA what will happen long-term (I think I'm already getting side-effects from long-term daily usage--high blood pressure, it used to be low; light-headed; muscle pain in one of the legs, I alternate each thigh-each injection, but one calf muscle tightens up--making it hard to walk)
Hide Full Comment

Reviewer: HunnyBunny78, 25-34 Female (Patient)

Comment:
This medicine so far has been the best that I have ever been treated with. I was in the ER and everything they were giving me through the IV just wasn't helping at all. When the nurse came in and said that the doctor order another dose of medication then she explained to me that it was a very potent drug called D.H.E. Then she reassured me that it wasn't a narcotic and as soon as she said that I w ... Show Full Comment

Comment:
This medicine so far has been the best that I have ever been treated with. I was in the ER and everything they were giving me through the IV just wasn't helping at all. When the nurse came in and said that the doctor order another dose of medication then she explained to me that it was a very potent drug called D.H.E. Then she reassured me that it wasn't a narcotic and as soon as she said that I was SOLD. At first I wasn't sure if it was going to work but she assured me after about 20 mins I should be doing fine. The only side effect that I had after she gave it to me was heart burn. If that is all I have to deal with to have a medication work on my migraines I WILL TAKE IT!!!!!
Hide Full Comment

Reviewer: Ja'aj, 65-74 Female on Treatment for 10 years or more (Patient)

Comment:
My first experience with D.H.E. 45 was in an E.R. in about 1986... I have gotten migraine since 1963. The protocol was Compazine I.V. first and 15 minutes later, the D.H.E.45, I.V. It was the first time in my life that I walked into an E.R. with a migraine, and walked out without it. My M.D. and my neurologist BOTH! wrote me perscriptions for the vials, so I could give myself the shot. ... Show Full Comment

Comment:
My first experience with D.H.E. 45 was in an E.R. in about 1986... I have gotten migraine since 1963. The protocol was Compazine I.V. first and 15 minutes later, the D.H.E.45, I.V. It was the first time in my life that I walked into an E.R. with a migraine, and walked out without it. My M.D. and my neurologist BOTH! wrote me perscriptions for the vials, so I could give myself the shot. I bought them 20 at a time. My veins "roll", so I wasn't going to mess with "I.V." I snapped the neck off the glass vial, drew the drug into a syringe, twisted around to the side, and gave myself a shot in my hip. (I.M.) (High, where all the fat is.) No lessons; I been getting shots for YEARS. I wasn't afraid of something I knew would stop that headache. And it did. It does. 40 minutes later; no headache. It works every time in 40 minutes. It never fails. I know it doesn't help everyone. Very few things do help "everyone". I tell EVERYONE I meet who have Migraine- about D.H.E 45. It surely helped me. It has taken the fear of that headache away. I used to -in the beginning- also load and inject Vistaril with the D.H.E. 45; to prevent possible nausea. I stopped taking the Vistaril after about 3 years. No nausea. I have -finally- almost stopped getting migraine. I don't miss it. I credit "outgrowing" them to some extent. Mostly I credit the D.H.E.45. It gave me back my life. The E.R. doctor told me that D. H. E. had been on the market for over 10 years when she mentioned it to me. She was surprised I han't heard of it. Thank God she had.
Hide Full Comment

Reviewer: cannonofski, 45-54 Female on Treatment for 10 years or more (Patient)

Comment:
This has been a wonder drug for me. My quality of life was in the toilet and I was facing not being able to hold a job because of the headaches. I finally found a neurologist that was willing to do whatever it took to find an answer. He taught me how to inject myself with DHE and 14 years later I still using it to relieve my headaches. I am sad to read that so many others have not had good exper ... Show Full Comment

Comment:
This has been a wonder drug for me. My quality of life was in the toilet and I was facing not being able to hold a job because of the headaches. I finally found a neurologist that was willing to do whatever it took to find an answer. He taught me how to inject myself with DHE and 14 years later I still using it to relieve my headaches. I am sad to read that so many others have not had good experiences with this drug. It has always successfully abated my pain within a couple of hours. Every other drug on the market proved worthless and terribly expensive.
Hide Full Comment