Skip to content

    Read user comments about the side effects, benefits, and effectiveness of Plaquenil oral.

    Overall User Ratings

    561 Total User Reviews

    User Reviews

    1-5 of 237 Next»
    Condition: Systemic Lupus Erythematosus
    11/15/2016 3:26:54 PM

    Reviewer: EnGee, 35-44 Female on Treatment for 1 to less than 2 years (Patient)

    Effectiveness

    Current Rating: 3

    Ease of Use

    Current Rating: 3

    Satisfaction

    Current Rating: 2

    Comment:
    My rhematologist placed me on plaquenil in winter of 2015 after experiencing a flare (40% of my hair fell out in 5 weeks and I was ALWAYS exhausted. Even if I slept it was unbearable). I've been on it a year, reluctantly. I do not want to have to be maintained on any chemicals or pills. Now that I've been on it a year the only thing that has improved is fatigue. But I"m not sure if it ... Show Full Comment

    Condition: Systemic Lupus Erythematosus
    10/26/2016 11:27:54 AM

    Reviewer: RK, 55-64 Male on Treatment for 1 to 6 months (Patient)

    Effectiveness

    Current Rating: 4

    Ease of Use

    Current Rating: 5

    Satisfaction

    Current Rating: 5

    Comment:
    Have been on this medication for 5 weeks. I believe it has reduced the severity of my symptoms by about half. I am concerned about the eye issues, but will keep a close watch going forward.

    Condition: Systemic Lupus Erythematosus
    9/15/2016 9:28:15 AM

    Reviewer: Aka sonny, 65-74 on Treatment for 1 to 6 months (Patient)

    Effectiveness

    Current Rating: 3

    Ease of Use

    Current Rating: 3

    Satisfaction

    Current Rating: 3

    Comment:
    I started at 700mg daily which I think puts me into an overdose situation. I experienced daily gastrointestinal problems. I informed doctor and he said to reduce to 600mg daily but the problem persisted. Now down to 400mg daily. Gastro problems not so severe now. My SLE symptoms were minor (Sjogren's symptoms primarily) and Prednisone actually solved it after a month. Now off the Prednis ... Show Full Comment

    Condition: Systemic Lupus Erythematosus
    1/11/2016 2:39:37 PM

    Reviewer: KatVJo, 19-24 on Treatment for 1 to less than 2 years (Patient)

    Effectiveness

    Current Rating: 5

    Ease of Use

    Current Rating: 5

    Satisfaction

    Current Rating: 4

    Comment:
    This medication relieved my joint pain, muscle weakness, myositis, pleuritic pain, and fatigue after about 2-3 months of starting the medication. I know this medication has bad reviews but after a few years of using the medication with a dose 600mg and above you risk these side effects. Plus Patients are supposed to get an eye exam every six moths while on medication to catch these sign early. I w ... Show Full Comment

    Condition: Systemic Lupus Erythematosus
    11/17/2015 3:48:32 PM

    Reviewer: screen name, 55-64 Female on Treatment for 10 years or more (Patient)

    Effectiveness

    Current Rating: 2

    Ease of Use

    Current Rating: 2

    Satisfaction

    Current Rating: 1

    Comment:
    I have systemic Lupus...took Plaquenil with great relief over 10 years...then woke up one morning and left eye COMPLETELY BLIND. Eye surgeon diagnosed RUPTURED RETINA...little to no chance of saving any sight w/surgery, but might hopefully keep from having the eye REMOVED due to eye shrinking from ruptured retina. Surgery has brought back SOME sight...but little. RUN FROM THIS MEDICATION!!! I h ... Show Full Comment

    1-5 of 237 Next»

    Ask the pharmacist

    Questions about medications? Get expert answers by video or live chat about allergies, pregnancy, sleep, and more.
    See the Ask the Pharmacist event schedule.

    Ask a Question

    Popular Slideshows & Tools on WebMD

    disciplining a boy
    Types, symptoms, causes.
    fruit drinks
    Eat these to think better.
    embarrassed woman
    Do you feel guilty after eating?
    diabetes highlighted
    4 early warning signs.
    handful of vegetables and vitamins
    Diet tips and mistakes.
    birth control pills
    Which kind is right for you?
    Remember your finger
    Are you getting more forgetful?
    sticky notes on face
    10 tips to clear your brain fog.
    Close up of eye
    12 reasons you're distracted.
    Trainer demonstrating exercise for RA
    Exercises for your joints.
    apple slices with peanut butter
    Each one takes 10 minutes or less.
    woman having a good day
    Revitalize your life.

    Newsletters

    Subscribe to free WebMD newsletters.

    • WebMD Daily

      WebMD Daily

      Subscribe to the WebMD Daily, and you'll get today's top health news and trending topics, and the latest and best information from WebMD.

    • Men's Health

      Men's Health

      Subscribe to the Men's Health newsletter for the latest on disease prevention, fitness, sex, nutrition, and more from WebMD.

    • Women's Health

      Women's Health

      Subscribe to the Women's Health newsletter for the latest on disease prevention, fitness, sex, diet, anti-aging, and more from WebMD.

    By clicking Submit, I agree to the WebMD Terms & Conditions & Privacy Policy and understand that I may opt out of WebMD subscriptions at any time.

    WebMD the app

    Get trusted health information. Whenever. Wherever... with your iPhone, iPad or Android.

    Find Out More
    IMPORTANT: About This Section and Other User-Generated Content on WebMD

    The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Some of these opinions may contain information about treatment or uses of drug products that have not been approved by the U.S. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment.

    Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately.