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3.2 Overall Rating

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Ease of Use

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Most voted positive review

50 People found this comment helpful

Wish I knew about this sooner!! No side effects what so ever. I am a 60 year old woman who had loss of sex drive, not to mention it hurt even if I tried. This made me feel like a 20 yr old again!!

Shared reviews and ratings

Carol | 55-64 | Female | On medication for less than 1 month | Patient
2/13/2024
Condition: Postmenopausal Urethral Atrophy
Overall rating 2.0
Effectiveness
Ease of Use
Satisfaction

After only one use I experienced blinding headaches, which I don't suffer from.I also felt extreme fatigue and generally unwell . Feelings of getting either candida or an UTI. I took for about 17 days ,even my pelvic gloom felt swollen and strange .Won't be taking anymore

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Lillie | 75 or over | Female | On medication for 10 years or more | Patient
1/16/2024
Condition: Postmenopausal Urethral Atrophy
Overall rating 3.0
Effectiveness
Ease of Use
Satisfaction

After using estradiol vaginal cream before bed, the next day I have more frequent trips to bathroom to urinate.almost feels like a UTI. Then the next day will be ok. I’ve been using the cream 10 years. Just noticing this side effect. Anyone else experiencing this?

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Anonymous |
10/27/2023
Condition: Other
Overall rating 2.0
Effectiveness
Ease of Use
Satisfaction

Doctor recommended this cream three times a week after i had my yearly exam. I started it in June 2023. Up to now October 2023 my hair is breaking off badly! And it turned curly in the back only. I can’t sleep at night at all. I stay awake till 3:30-4:00am. It makes it difficult for me to get up for work. I wish I would have NEVER put this in my body.

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disappointed | 75 or over | Female | On medication for 2 to less than 5 years | Patient
5/31/2023
Condition: Vaginal Inflammation due to Loss of Hormone Stimulation
Overall rating 2.3
Effectiveness
Ease of Use
Satisfaction

Been using Estradiol creams for several years. My pharmacy switched to this brand and I started to have problems. Cream worked for few weeks after opening new tube, then stops being effective. Happened with 3 different tubes, amd switching to different pharmacy to get different brand.

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DAW | 45-54 | Female | On medication for less than 1 month | Patient
3/1/2023
Condition: Painful Sexual Intercourse due to Menopause
Overall rating 1.7
Effectiveness
Ease of Use
Satisfaction

I got extreme allergic reaction after one suppository that led to urinary tract infection (UTI) the next day.

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June | 55-64 | Female | On medication for 1 to 6 months | Patient
12/3/2022
Condition: Other
Overall rating 3.3
Effectiveness
Ease of Use
Satisfaction

Messy on my panties, had to buy liners. I have developed breast nipple tenderness “Bad”. But I have noticed that I have had more Sexual arousal when my husband touches me between the legs ?? & that is Absolutely what I want going for! A Boost in my libido. Yea!!

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April | 55-64 | Female | On medication for less than 1 month | Patient
10/21/2022
Condition: Painful Sexual Intercourse due to Menopause
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

I am on my 2 weeks with the pill and I notice the difference the first time I used it! I am not dry down there like a sandbox and my husband also can tell the difference. I use the pill insert because it is less messy and I don’t have any luck with creams.

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Celia | 45-54 | Female | On medication for less than 1 month | Patient
10/17/2022
Condition: Postmenopausal Urethral Atrophy
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

Estradiol made me feel like I was on drugs. I used it for two nights and I felt the worst fatigue ever and it made my vagina burn and my face and lips was burning. I don't recommend this cream to no one. It's a killer

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HappyCamper | 55-64 | Female | On medication for less than 1 month | Patient
9/14/2022
Condition: Painful Sexual Intercourse due to Menopause
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

I have been using estradiol cream for about 3 weeks. I used 1 gm daily for 2 weeks and now I use 1 gram 3 to 4 times weekly. I had total relief from painful sec by the second week. My body feels normal and sex is enjoyable again. I would also like to mention that I had gone without sex for almost 20 yrs. I stopped having sex when I was 40. I am 59. I had started having menopause symptoms at 51. Just started being sexually active again in July, 2022. I found sex to be painful before estradiol even though I was not dry down there. I guess my vaginal walls had thinned. Now with estradiol I am back to normal. It is definitely worth it. I work out too. Dye my hair and looking good at 59. Feeling confident again.Read More Read Less

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Knightstar3770 | 45-54 | Female | On medication for less than 1 month | Patient
5/31/2022
Condition: Vaginal Inflammation due to Loss of Hormone Stimulation
Overall rating 2.3
Effectiveness
Ease of Use
Satisfaction

I took the medication 3x a week and developed and extreme rash that was both painful and itchy. My skin looked like raw meat, it was really bad.

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Grace | 65-74 | Female | On medication for 2 to less than 5 years | Patient
4/19/2022
Condition: Painful Sexual Intercourse due to Menopause
Overall rating 3.7
Effectiveness
Ease of Use
Satisfaction

After the initial loading dose, I am using 1 g 3x per week. It's an improvement, but wasn't sufficient for the atrophy. After a couple of months, the painful dryness improved, but I still couldn't tolerate a speculum for a pap smear, let alone sex. What tipped the balance to full function was sea buckthorn capsules (google sea buckthorn and vaginal atrophy to see "Effects of sea buckthorn oil intake on vaginal atrophy in postmenopausal women: a randomized, double-blind, placebo-controlled study") and the use of a vaginal dilator to stretch constricted tissue at the opening. Read More Read Less

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anonymous | 45-54 | Female | On medication for less than 1 month | Patient
1/27/2022
Condition: Painful Sexual Intercourse due to Menopause
Overall rating 2.3
Effectiveness
Ease of Use
Satisfaction

I got a yeast infection shortly after starting this. Apparently this is common, but after 6 weeks and 2 dr visits to clear it up, I am done with estrogen cream. I have switched to Vitamin E suppositories (often prescribed for cancer patients who can't get estrogen). I am in the perimenopause phase.

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Patti | 55-64 | Female | On medication for 1 to 6 months | Patient
12/18/2021
Condition: Vaginal Inflammation due to Loss of Hormone Stimulation
Overall rating 3.7
Effectiveness
Ease of Use
Satisfaction

I've been taking this medication for over a month. I'm not as dry as I was prior to taking it but my skin "between my labia majora & labia minora" still easily cracks/tears and is still irritable from time to time.

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JG Florida | 55-64 | Female | On medication for 6 months to less than 1 year | Patient
10/7/2021
Condition: Painful Sexual Intercourse due to Menopause
Overall rating 4.7
Effectiveness
Ease of Use
Satisfaction

Sex was painful and my sex drive was low. This started to work right away maybe a week after starting it. It was and is an amazing difference. I noticed no real side affects. I gained some weight after I started it but think it was due to just eating more junk food. I stopped doing that and lost the weight. I really appreciate this medication.

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L Pow | 55-64 | Female | On medication for 1 to 6 months | Patient
8/10/2021
Condition: Painful Sexual Intercourse due to Menopause
Overall rating 4.3
Effectiveness
Ease of Use
Satisfaction

This vaginal cream has helped me a lot and I am no longer dry. However, I have noticed weight gain. I’m up 8-10 pounds in just a few months.

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Di | 55-64 | Female | On medication for 6 months to less than 1 year | Patient
7/16/2021
Condition: Painful Sexual Intercourse due to Menopause
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

As others have said sex was no longer a great thing due to pain with intercourse. It took appx a month and I'm back to the old me :)

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Leesers | 55-64 | Female | On medication for less than 1 month | Patient
6/27/2021
Condition: Postmenopausal Urethral Atrophy
Overall rating 1.3
Effectiveness
Ease of Use
Satisfaction

Was told to apply a pea sized amount to the vaginal opening 3x weekly. "Just leave it at the opening with your finger, and your body will know what to do from there." It didn't. It should have melted towards the inside, but instead, it melted outside, covering the urethra. I had a mess every time I urinated after using the product.

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Anonymous | 65-74 | Female | On medication for 1 to less than 2 years | Patient
12/16/2020
Condition: Wasting of Tissues of the Vulva
Overall rating 2.3
Effectiveness
Ease of Use
Satisfaction

I stopped using this because I developed a sticky discharge. Now it persist, my underwear sticks to my body it's very annoying and uncomfortable. It doesn't itch or smell so it is not an infection.

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Anonymous | 65-74 | Female | On medication for 1 to less than 2 years | Patient
5/25/2020
Condition: Vaginal Inflammation due to Loss of Hormone Stimulation
Overall rating 3.7
Effectiveness
Ease of Use
Satisfaction

Caused itching on different parts of my body.

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havana | 55-64 | Female | On medication for 1 to 6 months | Patient
5/2/2018
Condition: Vaginal Inflammation due to Loss of Hormone Stimulation
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

Wish I knew about this sooner!! No side effects what so ever. I am a 60 year old woman who had loss of sex drive, not to mention it hurt even if I tried. This made me feel like a 20 yr old again!!

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