Reviewer: Cattleya, 75 or over Male on Treatment for 10 years or more (Caregiver)

Comment:
Possible Interaction of MULTAQ with NARDIL My wife has used Nardil with success for 30 years ; her present dose is 15 mg QID (60/d.)I am writing this to alert other Nardil users to an unexpected interaction with Multaq (dronedarone, Sanofi.) My wife experienced profound bradycardia (HR < 50 bpm), weakness and dyspnea after 5 doses (two days) on drug. After DX, she recovered over a 2 day period ... Show Full Comment

Comment:
Possible Interaction of MULTAQ with NARDIL My wife has used Nardil with success for 30 years ; her present dose is 15 mg QID (60/d.)I am writing this to alert other Nardil users to an unexpected interaction with Multaq (dronedarone, Sanofi.) My wife experienced profound bradycardia (HR < 50 bpm), weakness and dyspnea after 5 doses (two days) on drug. After DX, she recovered over a 2 day period to normal heart rate. The US FDA package insert is silent on MAOI's. International package inserts from the rest of the world contain a disclosure that MAOI's impede clearance by amine-oxidases of the active metabolite of Multaq, resulting in effective overdosage. We would not have started Multaq had we been aware of this issue. I have alerted both Sanofi and the US FDA of the need to harmonize with other agencies on this issue. As many Nardil users know, critical care physicians are too often unaware of serious Nardil interactions. I would recommend as a resource the free-text article by PK Gillman in British Journal Anaesthesia 95: 434 (2005)which deals with fatal risk to serotonin toxicity ("storms") following unwitting coadministration of many popular anaesthetics and pain-killers.
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Reviewer: freddy, 55-64 Male on Treatment for 1 to less than 2 years (Patient)

Comment:
this med has been good for me it has helped me recover from depression. but not with out help from the doctors.I Have been taken this for a year. the only side effect ive had is night sweats which has just started in the last week.

Comment:
this med has been good for me it has helped me recover from depression. but not with out help from the doctors.I Have been taken this for a year. the only side effect ive had is night sweats which has just started in the last week.
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Reviewer: Kansas depressed, 65-74 Male on Treatment for 10 years or more (Patient)

Comment:
Nardil is the only antidepressant that works for me. I have a genetic depression problem that is throughout my family. Nardil was only drug that worked for my mother. I have taken for 26 years and will probably take for the rest of my life. Without it I would have done myself in long ago. I thank God that it exists.

Comment:
Nardil is the only antidepressant that works for me. I have a genetic depression problem that is throughout my family. Nardil was only drug that worked for my mother. I have taken for 26 years and will probably take for the rest of my life. Without it I would have done myself in long ago. I thank God that it exists.
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Reviewer: Tracy, 45-54 Female on Treatment for 1 to 6 months (Patient)

Comment:
I have suffered from depression most of my adult life. Been on and off lots of different drugs and had huge success with Nardil, until the side effects kicked in. I haven't felt this good emotionally for years, but unfortunately I have to go off of it because I'm miserable physically. I have horrible tremors, my whole body shakes till I'm in so much pain I have to take pain meds, I've had uncontr ... Show Full Comment

Comment:
I have suffered from depression most of my adult life. Been on and off lots of different drugs and had huge success with Nardil, until the side effects kicked in. I haven't felt this good emotionally for years, but unfortunately I have to go off of it because I'm miserable physically. I have horrible tremors, my whole body shakes till I'm in so much pain I have to take pain meds, I've had uncontrolable diarrhea since I started it 4 months ago. I get so dehydrated I have to go to the ER for fluids regularly, I also have insomnia and terrible blood pressure issues. My blood pressure hasn't been above 90 over 60 since I started and it has gotten as low as 55 over 30 which obviously means a trip to the hospital. I'm so glad for those of you who don't have these problems. I wish I didn't because Nardil gave me my life back. If you are thinking about trying it I would say go for it. If I didn't have so many problems on it I would stay on it forever.
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Reviewer: 45-54 Female on Treatment for 1 to less than 2 years (Patient)

Comment:
With nardil I find I get tired after I take it.and what types of foods do i need to avoid

Comment:
With nardil I find I get tired after I take it.and what types of foods do i need to avoid
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