Buspirone/Itraconazole; Ketoconazole (mono deleted 04/17/2014)
Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Itraconazole and ketoconazole may slow down how quickly your liver processes buspirone.
What might happen:
The amount of buspirone in your blood may increase and cause more side effects than normal.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your doctor may want to decrease the dose of your buspirone while you are taking itraconazole or ketoconazole. Let your doctor know if you have excessive drowsiness, nausea, headaches, nervousness, lightheadedness, and/or excitement.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
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