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Drugs & Medications A-Z

delavirdine Oral

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Pimozide/Delavirdine; Efavirenz

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

When these medicines are taken together, your liver may processes your pimozide more slowly.

What might happen:

Your blood levels of pimozide may increase. This may result in an irregular heartbeat, which may be life-threatening.

What you should do about this interaction:

Contact your healthcare professionals (e.g. doctor or pharmacist) as soon as possible about taking these two medicines together.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

References:

1.Rescriptor (delavirdine mesylate) US prescribing information. Pharmacia & Upjohn Company August, 2012.
2.Sustiva (efavirenz) US prescribing information. Bristol-Myers Squibb Company August, 2012.
3.Orap (pimozide) US prescribing information. Gate Pharmaceuticals August, 2011.
4.Atripla (efavirenz/emtricitabine/tenofovir disoproxil fumarate) US prescribing information. Gilead Sciences, Inc. June, 2012.

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