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Sibling History of Blood Clots May Raise Your Risk

Study Shows Impact of Family History on Development of Deep Vein Thrombosis

Genetic Risk Factors for VTE

Five major genetic risk factors associated with an increased risk for VTE have been identified. But doctors do not routinely test for them, so most people do not know if they carry one or more of the genetic risk factors.

This was the case with NBC News correspondent David Bloom, who died of a blood clot that started in his legs and traveled to his lungs in the early days of the Iraq war after spending days immobilized in a tank while embedded with U.S. troops.

Although Bloom did not know it, he had inherited a blood clotting disorder that increased his risk for the dangerous blood clots, along with other risk factors, his wife, Melanie, later said.

Philadelphia cardiologist Don LaVan, MD, who is a spokesman for the American Heart Association, says the study confirms that asking patients about their family history of VTE is important for assessing risk.

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