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Epilepsy Health Center

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When Medical Marijuana Doesn’t Work


For those who move to Colorado and see no success, it can be heartbreaking.

“Everybody comes with a certain level of hope, of course. That’s why they’re here,” says Heather Jackson. She is the director of Realm of Caring, a nonprofit that helps families relocate to Colorado and get access to Charlotte’s Web, the type of medical marijuana developed for children with seizures.

“I think that is discouraging, but everybody is also realistic. These are families that have really been through the wringer. I’m sure they had hope for every remedy they’ve tried,” Jackson says. “We’re very upfront when folks get started and explain to them that this doesn’t work for everybody.”

A Cautionary Tale

More than 2.7 million Americans live with epilepsy. Many lead normal lives with the help of certain diets, surgery, or medication. After a diagnosis, a doctor will usually prescribe one drug, then another if it doesn’t work.

Among people who can’t control their seizures after trying three drugs, fewer than 1% will ever see a reduction in seizures from them, research shows. This includes 20% to 40% of those with epilepsy.

The consequences of uncontrolled childhood epilepsy can be dire. Seizures can delay or hinder brain development, leaving a person impaired for life. It can diminish success in school and lead to loneliness and isolation. Sudden unexplained death is 40 times more likely among people who continue to have seizures compared to those who are seizure-free.

Aiden, 8, has been on 17 different medications. He has a pacemaker-like device implanted near his collarbone to control the electrical impulses from the brain that cause seizures.

Nothing has worked to control the 300 grand mal seizures a month, caused by a rare form of epilepsy known as Dravet syndrome. He is developmentally disabled and has trouble walking or talking, says his mother, Nicole, of Castle Rock, CO.

Nicole tried high-CBD marijuana for Aiden, but his seizures increased. He began vomiting. After 11 months, she gave up.

“I’ve seen it working for other kids. I’m so glad we tried it. I’m so glad we live in a legal state and we had the opportunity to try it,” says Nicole, who also asked that her last name not be used. “It didn’t work for him, but it wasn’t worse than any of the other meds he was on.”

She sees her story as a cautionary tale for other desperate families willing to move to Colorado for a miracle cure.

“If they’re coming out thinking it’s going to be a miracle treatment that’s going to fix their children or make their wheelchair-bound child walk, I would say, ‘Hold on.’”

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