Lennox-Gastaut syndrome (LGS) is a rare and severe kind of epilepsy that starts in childhood. Children with LGS have seizures often, and they have several different kinds of seizures.
This condition is hard to treat, but researchers are looking for new therapies. Finding practical and emotional support is key to help you give your child the best quality of life while facing the challenges and stress this illness brings.
The seizures usually start between ages 2 and 6. Children with LGS have learning...
An electroencephalogram (EEG) to identify any abnormal electrical misfiring in the brain and help predict the risk of future seizures
Brain imaging tests such as an MRI or CT scan to help narrow down a possible treatable cause
A spinal tap if an infectious cause, such as meningitis, is suspected
What Are the Treatments for Seizures?
When a specific cause of the seizure is identified -- such as infection or low blood sugar -- treatment of that underlying condition often prevents seizures from recurring. If the underlying cause is not fully treatable or is unknown, treatment with anti-seizure (anticonvulsant) medications may be recommended.
Medications for Epilepsy
Anticonvulsant drugs can eliminate or reduce recurrent seizures. The choice of medication is based on the specific seizure type and pattern. Often, a single drug is used, but sometimes a combination may be necessary. Anticonvulsant drugs include:
Eslicarbazepine acetate (Aptiom)
Divalproex sodium (Depakote)
Oxteller XR (oxcarbazepine)
Valproic acid (Depakene)
For some drugs, your doctor may test your blood to make sure you are taking the right amount of medication. Blood tests can also make sure drugs are not affecting your kidneys or liver. Some people may be able to stop taking medication once their seizures have been under control for at least a year.
Surgery and Other Procedures for Seizures
Doctors may suggest surgery for the few patients whose seizures can't be controlled with medications. In vagus nerve stimulation, a device that electronically stimulates the vagus nerve (which controls activity between the brain and major internal organs) is implanted under the skin in the neck. This reduces seizure activity in some patients with partial seizures.