Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Erectile Dysfunction Health Center

Font Size

Taking Many Medications May Raise Risk of ED

Study: Men Who Take Multiple Medications May Have Increased Risk of Erectile Dysfunction
WebMD Health News
Reviewed by Laura J. Martin, MD

Nov. 15, 2011 -- The more medications a man takes, the more likely he will experience moderate or severe erectile dysfunction (ED), a new study shows.

The findings held even after researchers took into account underlying health problems.

The study is published online in the British Journal of Urology International.

Erectile dysfunction is the inability to achieve or maintain an erection suitable for sexual intercourse. It affects as many as 30 million U.S. men, according to the National Institutes of Health.

Exactly how taking multiple medications may increase risk for severe ED is not fully understood. But the findings suggest that tapering off unnecessary medications may be the first step in treating ED in some men.

"If you have difficulty with ED, consider curtailing any OTC medications that you don't need. And then really work with your doctor to see if you can cut down on any of your prescription medications," says study researcher Diana C. Londono, MD. She is a urologist at Kaiser Permanente Los Angeles Medical Center.

There are medications that treat ED, she says, but for these men, the first step is to look at what they are already taking to see if making some tweaks can improve the situation.

Tracking Use of Medication

Researchers tracked information about medication use among 37,712 men aged 45 to 69 years between 2002 and 2003.

Of these men, 29% said they had moderate or severe ED. The more medications the men took, the more likely they were to experience moderate or severe ED, the study showed.

Other risk factors for ED included older age, higher body mass index, diabetes, high cholesterol, high blood pressure, depression, and being a current or past smoker. The new findings concerning medication use and ED held even after the researchers took these factors into account.

Second Opinion

Joseph P. Alukal, MD, says that the study confirms that men who are sicker and/or are on more medications are more likely to have ED. He is an assistant professor of urology at the New York University School of Medicine.

On the flip side, ED may be an excellent window into someone's overall health.

It's a two-way street, Alukal says. Multiple medications and health problems can suggest ED, but ED can also help identify other related health problems, such as heart disease or diabetes.

"If you are struggling with ED, come in," he says. "We have great treatments that we did not have 10 to 15 years ago. But even more importantly, it can tell us something about your health."

Today on WebMD

handsome midadult man
11 tips to protect your erection.
man and woman on beach
How much do you know about ED?
stress in bed
Things that can deflate erections.
senior couple hugging
How medications work.
concerned man
stress in bed
Life Cycle of a Penis
Mens Body Problem
bored man
Lamm Erections Over Life
Food Men 10 Foods Boost Male Health
senior couple hugging

WebMD Special Sections