Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Erectile Dysfunction Health Center

Font Size

FDA Approves New Erectile Dysfunction Drug Stendra

Stendra Works Like Cialis, Levitra, Staxyn, Viagra
WebMD Health News
Reviewed by Laura J. Martin, MD

April 27, 2012 -- The FDA has approved Stendra (avanafil) for men with erectile dysfunction (ED).

Stendra, from Vivus Inc., is in the same drug class as the four oral ED drugs now on the U.S. market: Cialis, Levitra, Staxyn (an orally dissolving version of Levitra), and Viagra. An estimated 30 million U.S. men have ED, according to the FDA.

"This approval expands the available treatment options to men experiencing erectile dysfunction, and enables patients, in consultation with their doctor, to choose the most appropriate treatment for their needs," Victoria Kusiak, MD, deputy director of the Office of Drug Evaluation III in the FDA's Center for Drug Evaluation and Research, states in a news release.

In some participants in clinical trials, the drug was effective in as little as 15 minutes. Some men in clinical trials reported improved erections more than six hours after taking the drug.

In clinical trials, 77% of men with general ED were able to get erections after taking Stendra, compared to 54% of men taking an inactive placebo pill. Among men with diabetes-related ED, 63% were able to get erections after taking the drug, compared to 42% of men taking placebo.

Stendra resulted in successful intercourse for 57% of men with general ED (vs. 27% of men taking placebo) and for 40% of men with diabetes-related ED (vs. 20% of men taking placebo).

The main side effects of avanafil are similar to those of its sister drugs: headache, flushing, stuffy nose, and back pain. Rarely, an erection lasting for four or more hours may occur, which would need immediate medical attention. Other side effects occurring rarely include color vision changes, sudden loss of vision, and sudden loss of hearing. If sudden loss of vision or hearing occurs, it is recommended to call a doctor immediately.

Men who take nitrate medications should not take Stendra because the combination of these two medications can lead to a sudden drop in blood pressure.

Today on WebMD

handsome midadult man
11 tips to protect your erection.
man and woman on beach
How much do you know about ED?
stress in bed
Things that can deflate erections.
senior couple hugging
How medications work.
concerned man
stress in bed
Life Cycle of a Penis
Mens Body Problem
bored man
Lamm Erections Over Life
Food Men 10 Foods Boost Male Health
senior couple hugging

WebMD Special Sections