Skip to content

Erectile Dysfunction Health Center

Font Size

Medicines for Erection Problems: Reactions With Nitrate - Topic Overview

Phosphodiesterase-5 inhibitors, such as sildenafil (for example, Viagra), have revolutionized the treatment of erection problems (erectile dysfunction). But they can cause life-threatening side effects for anyone who also takes nitroglycerin or another medicine containing an organic nitrate. This combination can make your blood pressure fall too low, possibly leading to a stroke, a heart attack, or death. Do not take nitrate-containing medicines up to 24 hours after you take sildenafil (for example, Viagra) or vardenafil (for example, Levitra), or up to 48 hours after you take tadalafil (for example, Cialis).

Medicines that contain organic nitrates include:

Recommended Related to Erectile Dysfunction

High Blood Pressure and Erectile Dysfunction (ED)

To treat erectile dysfunction (ED), you have to lower high blood pressure. Some people are able to do that through lifestyle changes alone. Others need help from prescription high blood pressure medication. A problem for many men, though, is that some types of blood pressure drugs can causeerectile dysfunction. That may make it tough to stay on medication, especially if high blood pressure never caused any symptoms before. An estimated 70% of men who have side effects from high blood pressure medicine...

Read the High Blood Pressure and Erectile Dysfunction (ED) article > >

  • Nitroglycerin (such as Nitro-Dur, Nitrolingual, Nitrostat).
  • Isosorbide (such as Dilatrate, Isordil).
  • Nitroprusside (such as Nitropress).
  • Amyl nitrite or amyl nitrate (sometimes called "poppers"), which are sometimes abused.

Nitrates found in foods are not a danger when taking phosphodiesterase-5 inhibitors.

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Medical Reference from Healthwise

    Last Updated: May 14, 2012
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
    1
    Next Article:

    Medicines for Erection Problems: Reactions With Nitrate Topics

    Today on WebMD

    handsome midadult man
    11 tips to protect your erection.
    man and woman on beach
    How much do you know about ED?
     
    stress in bed
    Things that can deflate erections.
    senior couple hugging
    How medications work.
     
    concerned man
    Article
    stress in bed
    Slideshow
     
    Life Cycle of a Penis
    Article
    Mens Body Problem
    Slideshow
     
    bored man
    Article
    Lamm Erections Over Life
    Video
     
    Food Men 10 Foods Boost Male Health
    Article
    senior couple hugging
    Article
     

    WebMD Special Sections