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How Common Is Sjögren's Syndrome?

Sjögren's syndrome affects over one million people throughout the United States and is diagnosed in women and men of all races. Rarely occurring in children, Sjögren's syndrome is most common in white women who are in their 40s and 50s. Nine times more women than men have Sjögren's syndrome.1

Sjögren's syndrome may develop in a person who has a connective tissue disorder, such as rheumatoid arthritis, lupus, or scleroderma, and is then classified as secondary Sjögren's syndrome. Secondary Sjögren's syndrome develops in 10% to 25% of people with lupus and in 30% to 50% of people with rheumatoid arthritis.2

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  1. Jonsson R, et al. (2005). Sjögren's syndrome. In WJ Koopman, LW Moreland, eds., Arthritis and Allied Conditions: A Textbook of Rheumatology, 15th ed., vol. 2, pp. 1681-1705. Philadelphia: Lippincott Williams and Wilkins.

  2. Naguwa S, Gershwin ME (2008). Sjögren's syndrome. In L Goldman, D Ausiello, eds., Cecil Textbook of Medicine, 23rd ed., chap. 289, pp. 2041-2045. Philadelphia: Saunders.

By Healthwise Staff
Primary Medical Reviewer Anne C. Poinier, MD - Internal Medicine
Specialist Medical Reviewer Stanford M. Shoor, MD - Rheumatology
Last Revised May 4, 2010

WebMD Medical Reference from Healthwise

Last Updated: May 04, 2010
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

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