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Wet Age-Related Macular Degeneration

Wet age-related macular degeneration (wet AMD) is far less common but much more harmful to a person's vision than dry AMD. Only about 1 out of 10 people with macular degeneration has wet AMD.1 But wet AMD accounts for 9 out of 10 cases of blindness caused by the disease.2

Doctors may also refer to wet AMD as neovascular, exudative, or disciform AMD.

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Wet AMD often develops in areas of dry AMD when breaks develop in the deeper layers of the retina and abnormal blood vessels grow into these breaks (choroidal neovascularization). The abnormal blood vessels are fragile and leak blood and fluid under the macula. They also cause abnormal scar tissue to form under the macula and distort the shape and position of the macula.

  • Wet AMD may affect one or both eyes.
  • Vision loss usually develops rapidly.
  • Vision loss is often severe and always permanent.

People rarely go completely blind from the disease, because it does not affect side (peripheral) vision. But wet AMD can cause a severe or even a total loss of central vision. In some cases, treatment may slow down or delay vision loss. But treatment is not usually effective over the long term.

Citations

  1. Arnold J, Heriot W (2007). AMD, search date March 2006. Online version of BMJ Clinical Evidence: http://www.clinicalevidence.com.

  2. American Academy of Ophthalmology (2008). Age-Related Macular Degeneration (Preferred Practice Pattern). San Francisco: American Academy of Ophthalmology. Available online: http://one.aao.org/CE/PracticeGuidelines/PPP.aspx.

ByHealthwise Staff
Primary Medical ReviewerE. Gregory Thompson, MD - Internal Medicine
Specialist Medical ReviewerSteven T. Charles, MD - Ophthalmology
Last RevisedJuly 20, 2011

WebMD Medical Reference from Healthwise

Last Updated: July 20, 2011
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

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