Skip to content

    Eye Health Center

    Font Size
    A
    A
    A

    New Drug for Rare Type of Macular Degeneration.

    Drug Slows Vision Loss in Wet Age-Related Macular Degeneration
    By
    WebMD Health News

    Dec. 21, 2004 -- The FDA has approved a new drug treatment for wet age-related macular degeneration. The drug, called Macugen, doesn't cure the condition, but it slows vision loss.

    Wet age-related macular degeneration (wet AMD) is rare. It accounts for about 1 in 10 cases of macular degeneration. But when it strikes, it can devastate sight. It's estimated that wet AMD causes 90% of blindness related to macular degeneration.

    Wet AMD is caused by the growth of abnormal, leaky blood vessels in the eye. The blood and fluid that escape from the blood vessels damage the eye. Central vision, which is required for activities like reading, driving, and recognizing faces, can be severely affected or even destroyed by the disease.

    If untreated, people with wet age-related macular degeneration may become functionally blind. However, they rarely become totally blind, since wet AMD doesn't affect peripheral vision.

    "Macugen provides a needed addition to the treatment of patients with this disease," says acting FDA Commissioner Lester Crawford, DVM, PhD, in a news release.

    Macugen's safety and effectiveness was tested in two trials for two years. In both studies, vision loss slowed significantly in wet AMD patients receiving Macugen.

    The recommended dose is 0.3 milligrams administered once every six weeks by injection to the eye, say the drug's makers, Eyetech Pharmaceuticals and Pfizer, a WebMD sponsor.

    Serious side effects from the injection procedure included infections, retinal detachment, and traumatic cataract, says the FDA. Other frequently reported side effects included eye irritation, eye pain, bleeding under the eye's outer membrane, and blurred vision.

    Today on WebMD

    Woman holding tissue to reddened eye
    Learn about causes, symptoms, and treatments.
    eye
    Simple annoyance or the sign of a problem?
     
    red eyes
    Symptoms, triggers, and treatments.
    blue eye with contact lens
    Tips for wearing and caring.
     
    Understanding Stye
    Article
    human eye
    Article
     
    eye
    Video
    eye exam timing
    Video
     
    vision test
    Tool
    is vision correction surgery for you
    Article
     
    high tech contacts
    Article
    eye drop
    Article