Cyclobenzaprine for Fibromyalgia
How It Works
Cyclobenzaprine is a drug used to relax muscles. Experts do not know exactly how this drug works to improve fibromyalgia.
Why It Is Used
Doctors may prescribe cyclobenzaprine to treat the pain, stiffness, and sleep problems that occur with fibromyalgia.
How Well It Works
People with fibromyalgia who take cyclobenzaprine seem to notice an overall improvement in their symptoms. And they especially note improved sleep.1 The medicine's effects may decrease over time.
Side effects include:
Less common side effects include fatigue, weakness, nausea, constipation, stomach upset, blurred vision, nervousness, and confusion.
See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)
What To Think About
It is difficult to measure improvements in painful diseases like fibromyalgia. This makes it hard to tell how effective a drug is in treating this condition.
Complete the new medication information form (PDF)(What is a PDF document?) to help you understand this medication.
Tofferi JK, et al. (2004). Treatment of fibromyalgia with cyclobenzaprine: A meta-analysis. Arthritis and Rheumatism, 51(1): 9-13.
Primary Medical ReviewerAnne C. Poinier, MD - Internal Medicine
Specialist Medical ReviewerKarin M. Lindholm, DO - Neurology
Current as ofMarch 12, 2014