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    Cyclobenzaprine for Fibromyalgia

    Examples

    Generic Name Brand Name
    cyclobenzaprine Amrix

    How It Works

    Cyclobenzaprine is a drug used to relax muscles. Experts do not know exactly how this drug works to improve fibromyalgia.

    Why It Is Used

    Doctors may prescribe cyclobenzaprine to treat the pain, stiffness, and sleep problems that occur with fibromyalgia.

    How Well It Works

    People with fibromyalgia who take cyclobenzaprine seem to notice an overall improvement in their symptoms. And they especially note improved sleep.1 The medicine's effects may decrease over time.

    Side Effects

    Side effects include:

    Less common side effects include fatigue, weakness, nausea, constipation, stomach upset, blurred vision, nervousness, and confusion.

    See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

    What To Think About

    It is difficult to measure improvements in painful diseases like fibromyalgia. This makes it hard to tell how effective a drug is in treating this condition.

    Complete the new medication information form (PDF)(What is a PDF document?) to help you understand this medication.

    Citations

    1. Tofferi JK, et al. (2004). Treatment of fibromyalgia with cyclobenzaprine: A meta-analysis. Arthritis and Rheumatism, 51(1): 9-13.

    ByHealthwise Staff
    Primary Medical ReviewerAnne C. Poinier, MD - Internal Medicine
    Specialist Medical ReviewerKarin M. Lindholm, DO - Neurology

    Current as ofMarch 12, 2014

    WebMD Medical Reference from Healthwise

    Last Updated: March 12, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

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