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    CSPI States That Caramel Coloring Produced With Ammonia Contains 2 Carcinogens

    Feb. 16, 2011 -- Two types of caramel coloring used in some sodas and foods contain two carcinogens and should be banned, according to the nonprofit Center for Science in the Public Interest (CSPI).

    “We are calling on the FDA to ban the use of caramel coloring in colas and certain other foods,” CSPI Executive Director Michael F. Jacobson said during a teleconference.

    The caramel coloring used in some sodas is manufactured via a chemical reaction between sugars, ammonia, and sulfates. These reactions produce the two carcinogens: 2-methylimidazole (2-MEI) and 4-methylimidazole (4-MEI), he says. These chemicals have been shown to cause cancer in mice and rats.

    Representatives from the beverage industry and from the Coca-Cola Company reject the claims that the additives are dangerous, and Coca-Cola notes in a statement to WebMD that 4-MEI "forms normally in the ‘browning reaction’ while cooking, even in one’s own kitchen."

    Jacobson says that 2-MEI and 4-MEI "are not potent carcinogens, but it is totally inappropriate to accept any risk from artificial coloring that has no nutritional or preservative value."

    Natural alternatives -- including dark colorings from beets or carrots -- do exist, he says. Alternatively, the soda industry could market clear colas.

    Next Steps?

    The FDA will now review the petition. “The FDA moves slowly and I suspect that they will try to persuade the industry to use natural coloring,” Jacobson says.

    California has added 4-MEI to its list of carcinogens and is pursuing legislation that requires any product containing elevated levels to carry a warning label. For 4-MEI, levels higher than 16 micrograms per person per day from an individual product would require a warning.

    Jacobson says some sodas have 4-MEI levels more than eight times higher than that. “The level is quite significant,” he says.

    The sugar in regular soda does pose a greater health threat than these two chemicals, he says. But “if you are looking for yet another reason to avoid soda pop, this is a good one,” he says. “Soda has 10 teaspoons of sugar, artificial sweeteners, caffeine, and a sprinkling of carcinogens,” he says.

    Jeff Stier, a senior fellow at the Washington-D.C. based National Center for Public Policy Research, follows health and science issues. “You cannot make firm conclusions about human health based on animal studies,” he says.

    Stier says this is part of a campaign against soda and has nothing to do with carcinogens and cancer. “Limiting sugary soda is a good idea,” he says. “Diet sodas are a great substitute for people watching their weight.”

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