If the herpes simplex virus (HSV) invades a part of the body other than the genital area, it may cause disease in that part of the body. In general, complications are rare. And they usually occur with the first-time (primary) genital herpes outbreak. Some of these complications include:
Meningitis, an infection of the fluid (cerebrospinal fluid, or CSF) and tissues (meninges) that surround the brain and spinal cord.
The eyes (herpes keratitis). Herpes can be transmitted from the mouth or genitals to the eyes. This can cause blindness if it is not treated early. If your eye is very irritated or if you feel pain in your eye, see your doctor as soon as possible.