Healthy Aging Health Center
This article is from the WebMD News Archive
Fidget Your Way to Longer Life
July 11, 2006 -- Even the simplest physical activity may lengthen lives -- no sweating required, new research shows. In fact, mundane physical activity like household chores may count.
Sound too good to be true? That's the finding from the National Institute on Aging's Todd Manini, PhD, and colleagues.
"Simply expending energy through any activity may influence survival in older adults," they write in The Journal of the American Medical Association's July 12 issue.
Does their theory hold water? Perhaps, says a journal editorial. Manini's finding on longevity motion is "provocative and if documented by future research would have major implications for physical activity recommendations," the editorialists write.
Active Elders
Manini's team studied 302 healthy adults in Pittsburgh and Memphis who were 70 to 82 years old. When the study started, participants said they had no problem climbing at least 10 stairs, walking 0.4 kilometers, or performing basic daily chores.
Researchers first checked how much carbon dioxide each participant typically exhaled.
Greater activity means greater carbon dioxide production, the researchers reasoned. Think of a sprinter panting hard after a race, compared to the calm, even breathing of a spectator watching the race.
To measure carbon dioxide production, participants drank a glass of water with "labeled" hydrogen and oxygen. Over the next four hours, the researchers checked participants' urine and blood samples to determine carbon dioxide production and total energy expenditure (amount of calories burned per day).
Participants took the carbon dioxide test twice, two weeks apart.
Calories Burned, Death Rate
The researchers then calculated how many calories each of the participants burned per day. Every calorie counted, whether it was burned in formal exercise or in digestion, household chores, or simply fidgeting.
Participants also rated their own health and reported their physical activities, whether mild (such as walking) or vigorous (jogging, for instance).
After that, their only obligation was taking two yearly phone calls -- over an average of six years -- from the researchers.
Those phone calls had a simple purpose: See which participants were still alive. Year after year, most participants picked up the phone when the researchers called. But 55 participants -- about 18% of the entire group -- died during the follow-up period.
Movers Live Longer
The most physically active participants were nearly 70% less likely to die than those with the lowest physical activity level. Self-rated health, education, smoking status, and health conditions at the study's start scarcely changed the results.
The odds of dying during the study were 12% for the most active group, nearly 18% for those with medium physical activity levels, and nearly 25% for the least active group, the study shows.
Many studies have linked physical activity to better health. That's one reason the CDC recommends everyone get at least 30 minutes of moderate-intensity physical activity at least five days per week.
But this particular project had a twist the researchers didn't expect: The most active participants didn't give themselves enough credit.
Indication
Uroxatral® (alfuzosin HCl 10 mg extended-release tablets) is an alpha1-blocker for the treatment of the signs and symptoms of BPH.
Important Safety Information
Do not take UROXATRAL if you have liver problems or if you are taking antifungal drugs like ketoconazole or itraconazole, or HIV drugs like ritonavir.
UROXATRAL can cause a sudden drop in blood pressure, especially when starting treatment. This may lead to fainting, dizziness, and lightheadedness. Do not drive, operate machinery, or do any dangerous activity until you know how UROXATRAL will affect you. This is especially important if you already have a problem with low blood pressure or take medicines to treat high blood pressure. There may be an increased risk of low blood pressure and fainting when taking UROXATRAL in combination with blood pressure medication or nitrates.
Before taking UROXATRAL, tell your doctor if you have kidney problems.
Also, tell your doctor if you or any family member(s) have or take medications for a rare heart condition known as congenital prolongation of the QT interval.
BPH and prostate cancer can cause the same symptoms. However, UROXATRAL is not a treatment for prostate cancer.
The most common side effects with UROXATRAL are dizziness, upper respiratory tract infection, headache, and tiredness.
Please see UROXATRAL patient information.



