Heart Disease Health Center
Beta-blockers for coronary artery disease
Examples
| Generic Name | Brand Name |
|---|---|
| acebutolol | Sectral |
| atenolol | Tenormin |
| carvedilol | Coreg |
| labetalol | Trandate |
| metoprolol | Lopressor, Toprol |
| nadolol | Corgard |
| penbutolol | Levatol |
| pindolol | |
| propranolol | Inderal |
| timolol |
How It Works
Beta-blockers reduce the workload on the heart by slowing the heart rate. A more rapid heart rate caused by exertion and excitement increases the workload on the heart.
Why It Is Used
Beta-blockers lower heart rate and blood pressure and reduce the workload on the heart. This in turn can help relieve or prevent chest pain (angina). Beta-blockers are often used with other medications to treat a heart attack in progress.
Beta-blockers are also taken after a heart attack for a long time-maybe for the rest of your life-to lower the risk of sudden death.
How Well It Works
Beta-blockers can reduce the severity and frequency of angina. If you are at an increased risk for a heart attack and sudden death, beta-blockers can reduce this risk; you are less likely to have another heart attack if you are taking a beta-blocker. 1
Beta-blockers are the first medications considered for use in people who have coronary artery disease and stable angina. 1 They also may help control unstable angina symptoms in some people.
Side Effects
Side effects of beta-blockers may include:
- Fatigue.
- Erection problems (impotence).
- Decreased blood flow to the extremities, causing them to feel cold; increased leg pain brought on by exertion (intermittent claudication).
- In people who have diabetes, beta-blockers can cover up warning signs of low blood sugar (hypoglycemia), such as change in pulse rate, and increase the risk of low blood sugar episodes.
See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)
What To Think About
Beta-blockers may worsen other medical conditions, such as asthma, heart failure, diabetes, and certain heart arrhythmias. You may have to stop taking beta-blockers if side effects develop and persist.
Because beta-blockers can make you feel tired, they may add to feelings of depression.
Complete the new medication information form (PDF)
(What is a PDF document?)
to help you understand this medication.
Citations
Snow V, et al. (2004). Primary care management of chronic stable angina and asymptomatic suspected or known coronary artery disease: A clinical practice guideline from the American College of Physicians. Annals of Internal Medicine, 141(7): 562–567. Also available online: http://www.annals.org/cgi/reprint/141/7/562.pdf.
WebMD Medical Reference from Healthwise
