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Heart Disease Health Center

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Brain Natriuretic Peptide (BNP) Test

How It Feels

You may feel nothing at all from the needle puncture, or you may feel a brief sting or pinch as the needle goes through the skin. Some people feel a stinging pain while the needle is in the vein. But many people do not feel any pain (or have only minor discomfort) once the needle is positioned in the vein. The amount of pain you feel depends on the skill of the health professional drawing the blood, the condition of your veins, and your sensitivity to pain.


There is very little risk of complications from having blood drawn from a vein.

  • You may develop a small bruise at the puncture site. You can reduce the risk of bruising by keeping pressure on the site for several minutes after the needle is withdrawn.
  • In rare cases, the vein may become inflamed after the blood sample is taken. This condition is called phlebitis and is usually treated with a warm compress applied several times daily.
  • Continued bleeding can be a problem for people with bleeding disorders. Aspirin, warfarin (Coumadin), and other blood-thinning medicines can also make bleeding more likely. If you have bleeding or clotting problems, or if you take blood-thinning medicines, tell your health professional before your blood is drawn.


A brain natriuretic peptide (BNP) test measures the amount of the BNP hormone in the blood. BNP values tend to increase with age and are higher in women than men.

The normal values listed here-called a reference range-are just a guide. These ranges vary from lab to lab, and your lab may have a different range for what's normal. Your lab report should contain the range your lab uses. Also, your doctor will evaluate your results based on your health and other factors. This means that a value that falls outside the normal values listed here may still be normal for you or your lab.

Brain natriuretic peptide 1


0-99 picograms per milliliter (pg/mL) or 0-99 nanograms per liter (ng/L)

The amount of a related substance, called N-terminal pro brain-natriuretic peptide (NT-proBNP), may be measured instead of BNP. The results from the NT-proBNP test are different than those from the BNP test but provide similar information.

High values

A high value of BNP in the blood:

  • Means an increased amount of fluid or high pressure inside the heart.
  • May be used to help determine the severity of heart failure.
  • May mean a higher chance of death in people with heart failure.
  • May show early heart failure in people on kidney dialysis.

WebMD Medical Reference from Healthwise

Last Updated: March 12, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

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