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Catecholamines in Urine

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Normal urine values may vary in children depending on their age.

High values

  • High levels of free catecholamines, vanillylmandelic acid (VMA), or metanephrine can mean an adrenal gland tumor (pheochromocytoma) or another type of tumor that makes catecholamines is present.
  • Any major stress, such as burns, a whole-body infection (sepsis), illness, surgery, or traumatic injury, can cause high catecholamine levels.
  • Many blood pressure medicines can also cause high catecholamine levels.

Low values

Low values may be caused by diabetes or some nervous system problems.

What Affects the Test

Reasons you may not be able to have the test or why the results may not be helpful include:

  • Doing physical exercise.
  • Having extreme emotional stress.
  • Having surgery, injury, or illness.
  • Taking certain medicines, such as aspirin, nitroglycerin, tricyclic antidepressants, tetracycline, theophylline, or some blood pressure medicines.
  • Using nicotine, alcohol (ethanol), or cocaine.
  • Taking nonprescription cough, cold, or sinus medicines.
  • Eating or drinking foods with caffeine.

What To Think About

  • The 24-hour urine test is better for finding high levels of catecholamines than a blood test. To learn more about a catecholamine blood test, see the topic Catecholamines in Blood.

Citations

  1. Fischbach FT, Dunning MB III, eds. (2009). Manual of Laboratory and Diagnostic Tests, 8th ed. Philadelphia: Lippincott Williams and Wilkins.

Other Works Consulted

  • Chernecky CC, Berger BJ (2008). Laboratory Tests and Diagnostic Procedures, 5th ed. St. Louis: Saunders.

  • Fischbach FT, Dunning MB III, eds. (2009). Manual of Laboratory and Diagnostic Tests, 8th ed. Philadelphia: Lippincott Williams and Wilkins.

  • Pagana KD, Pagana TJ (2010). Mosby’s Manual of Diagnostic and Laboratory Tests, 4th ed. St. Louis: Mosby Elsevier.

By Healthwise Staff
Primary Medical Reviewer E. Gregory Thompson, MD - Internal Medicine
Specialist Medical Reviewer Alan C. Dalkin, MD - Endocrinology
Current as of June 20, 2012
1 | 2 | 3

WebMD Medical Reference from Healthwise

Last Updated: June 20, 2012
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

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