Clogged Arteries (Arterial Plaque)

Arteries are blood vessels that carry blood rich in oxygen throughout your body. They go to your brain as well as to the tips of your toes. Healthy arteries have smooth inner walls and blood flows through them easily. Some people, however, develop clogged arteries. Clogged arteries result from a buildup of a substance called plaque on the inner walls of the arteries. Arterial plaque can reduce blood flow or, in some instances, block it altogether.

Clogged arteries greatly increase the likelihood of heart attack, stroke, and even death. Because of these dangers, it is important to be aware, no matter how old you are, of the causes of artery plaque and treatment strategies to prevent serious consequences.

What causes arterial plaque?

Plaque that accumulates on the inner walls of your arteries is made from various substances that circulate in your blood. These include calcium, fat, cholesterol, cellular waste, and fibrin, a material involved in blood clotting. In response to plaque buildup, cells in your artery walls multiply and secrete additional substances that can worsen the state of clogged arteries.

As plaque deposits grow, a condition called atherosclerosis results. This condition causes the arteries to narrow and harden.

Although experts don’t know for sure what starts atherosclerosis, the process seems to stem from damage to the arterial wall. This damage, which enables the deposition of plaque, may result from:

  • High ''bad'' cholesterol and low ''good'' cholesterol. High levels of ''bad'' cholesterol, or low-density lipoprotein (LDL), are major contributors to arterial plaque formation. But that doesn’t tell the whole story. Everyone also has ''good'' cholesterol, or high-density lipoprotein (HDL), circulating in the blood. HDL is believed to remove some of the bad cholesterol from plaque in clogged arteries and transport it back to the liver, where it is eliminated.
  • High blood pressure . Having high blood pressure increases the rate at which arterial plaque builds up. It also hastens the hardening of clogged arteries.
  • Cigarette smoke. Cigarette smoke seems to increase the rate of atherosclerosis in the arteries of the heart, legs, and the aorta -- the largest artery in the body.
  • Diabetes, or elevated circulating blood sugaris also a major culprit. Even people who have elevated sugars not yet at the level of diabetes, such as seen in the metabolic syndrome, also have increased risk of plaque formation.

Plaque often starts to develop during the childhood or teenage years. Then clogged arteries develop in middle age or later.

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What are the dangers of arterial plaque and clogged arteries?

It depends on where arterial plaque accumulates. Clogged arteries in different parts of the body can lead to multiple medical conditions, including:

  • Coronary artery disease. When plaque accumulates in the arteries carrying blood to the heart, it results in coronary artery disease, or heart disease. This condition can lead to heart attacks and is one of the leading causes of death in the United States.
  • Carotid artery disease . The carotid arteries run up either side of your neck. They supply oxygen to your brain. The accumulation of arterial plaque in the carotid arteries can lead to stroke.
  • Peripheral artery disease. If plaque builds up in the blood vessels that carry blood to your legs, it can reduce the amount of oxygen delivered. The reduced blood flow can cause you to experience pain, numbness, or serious infection in your legs and feet.

Do clogged arteries cause any symptoms?

In many instances, clogged arteries do not cause any symptoms until a major event, such as a heart attack or stroke, occurs.

At other times, especially when the the artery is blocked by 70% or more, the buildup of arterial plaque may cause symptoms that include:

The first symptom, chest pain, is also called angina. It may result from reduced blood flow to the heart. That reduced blood flow is caused by plaque in the arteries leading to the heart.

Clogged arteries in carotid artery disease may cause stroke precursors known as transient ischemic attacks, or TIAs. TIAs may produce the following symptoms:

  • Sensation of weakness or numbness on one side of your body
  • Inability to move an arm or a leg
  • Loss of vision on one side only
  • Slurring of words

Clogged arteries in peripheral artery disease may cause:

Are there tests for clogged arteries?

Yes. There are several tests for clogged arteries. Your doctor will determine which tests to prescribe based on your symptoms and medical history. The tests may include:

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How are clogged arteries or arterial plaque treated?

There are a variety of prevention and treatment options for clogged arteries. What your doctor prescribes to reduce arterial plaque and prevent clogged arteries will depend on the severity of your condition and your medical history. Your doctor may prescribe one or more of the following:

1. Lifestyle changes. A healthy lifestyle is essential for the management of arterial plaque and treatment of clogged arteries. This includes:

2. Surgical procedures. In some instances, surgery may be necessary to treat clogged arteries and prevent additional arterial plaque accumulation. Surgery may include:

  • Stent placement. A small tube called a stent, which may contain medication, can be placed in an artery to maintain adequate blood flow.
  • Bypass surgery. In this operation, arteries from other parts of the body are moved to bypass clogged arteries and help oxygen-rich blood reach its target destination.
  • Balloon angioplasty. This procedure helps open clogged arteries that have become partially or fully blocked.

3. Medications. A number of medications may help control some of the factors that contribute to the accumulation of arterial plaque. These include:

  • Cholesterol-lowering drugs
  • Blood pressure-lowering drugs
  • Aspirin and other blood-thinning drugs, which reduce the likelihood of dangerous blood clot formation
WebMD Medical Reference Reviewed by Suzanne R. Steinbaum, MD on September 28, 2014

Sources

SOURCES:

American Heart Association: ''Atherosclerosis.''

U.S. Food and Drug Administration: ''Atherosclerosis.''

American Heart Association: ''Peripheral Heart Disease.''

National Heart Lung and Blood Institute: ''Atherosclerosis.''

WebMD Medical Reference: ''Coronary Artery Disease.''

Society for Vascular Surgery, VascularWeb: ''Carotid Artery Disease, Stroke, Transient Ischemic Attacks.''

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