Clot buster drugs, or thrombolytic therapy, are a type of heart medication given in the hospital through the veins (intravenous) to break up blood clots. Heart attack (caused by a blood clot in a coronary artery) and ischemic stroke (caused by a blood clot in an artery in the brain) are the two main conditions for which clot busters are used.
In the battle against atherosclerosis, the stakes remain high. Scientists
have made exciting medical advances, but the disease persists as a leading
cause of illness and death in the United States. This year alone,
atherosclerosis will contribute to about 1.2 million heart attacks among
“While we have very good therapies and tests to identify the disease and
predict the risk, none of them is perfect,” says Stephen Nicholls, MBBS
(bachelor of medicine/surgery), PhD, clinical director...
To break up blood clots in other blood vessels in the body.
It is important to know the signs and symptoms of stroke and heart attack and call for emergency help (9-1-1 in most areas) right away if you or someone you are with is experiencing them. The faster you receive treatment with thrombolytic therapy (if appropriate), the quicker blood flow will be restored to the area and the greater the chance to prevent long-term damage, or even death.
There are several drugs that have been developed to break up clots, such as:
Tissue plasminogen activator (TPA)
Who Shouldn't Take Clot Busters?
Some people aren't able to take clot busters. Please tell your doctor if you have any of the following conditions:
Previous hemorrhagic stroke or bleeding in the brain
Recent trauma, falls, or blows to the head within the past 3 months
Active peptic ulcer
Should I Be Concerned About Food and Drug Interactions With Clot Busters?
Certain drugs may increase your risk of bleeding if you are prescribed clot busters. Tell your doctor the names of all the medications, over-the-counter drugs, herbal medications, supplements, or vitamins you are taking. Examples of these medications include: