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Heart Disease Health Center

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Heart Disease and Treatment With Digoxin

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Should I Be Concerned About Food and Drug Interactions With Digoxin?

Digoxin is often prescribed along with diuretics (water pills), an ACE inhibitor or an angiotensin receptor blocker (ARB), and a beta-blocker for the treatment of heart failure. If you have more side effects after taking your medications together, contact your doctor. You may need to change the times you are taking each medication.

If you are taking the cholesterol-lowering drugs Questran or Questran Light (cholestyramine) or Colestid (colestipol), take them at least two hours after digoxin to prevent interactions.

Check with your doctor before taking the following over-the-counter medications, as they can interfere with the effects of digoxin: antacids; asthma drugs; cold, cough or sinus medicine; laxatives; medicines for diarrhea; or diet drugs.

Follow your doctor's dietary advice by limiting sodium in your daily diet to 2,000 mg or less per day. Talk to your doctor about how much potassium you should get.

Can Pregnant Women Take Digoxin?

Women on digoxin should tell their doctor if they are pregnant or become pregnant. Digoxin is classified as a pregnancy category "C" medicine, which means that it is unknown if the drug has any effect on pregnancy. It should be given only if the benefit to you outweighs the potential risk to the baby.

Digoxin can be passed to a nursing baby through breast milk, the effect of which is not clear. Women on digoxin who are planning to breastfeed should consult their doctor.

Can Children Take Digoxin?

The side effects of digoxin do not appear to be different in children. Parents should discuss the benefits and risk of having their child take digoxin with their child's doctor.

Can Elderly People Take Digoxin?

Elderly people on digoxin tend to have more frequent side effects. Generally, elderly people taking this drug will require a lower dose.

WebMD Medical Reference

Reviewed by James Beckerman, MD, FACC on March 21, 2015
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