Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier
WebMD

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started
My Medicine
WebMD

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion
    WebMD

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community
    WebMD

    Community

    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Heart Failure Health Center

Font Size
A
A
A

Underused Treatments Could Save Lives From Heart Failure

Study Shows Thousands of Lives Could Be Saved From Treatments Such as Beta-Blockers
By
WebMD Health News
Reviewed by Laura J. Martin, MD

June 8, 2011 -- Close to 70,000 heart failure deaths could be prevented in the U.S. each year if more patients were on recommended therapies, new research suggests.

The study is among the first to quantify the impact, in terms of lives saved, of broader use of drug and cardiac device treatments for heart failure.

About 6 million people in the U.S. have heart failure and roughly 282,000 die of the disease each year, according to the CDC.

The condition occurs when the heart is unable to pump enough blood and oxygen to other organs. Common symptoms include shortness of breath during normal activity, water retention leading to swelling, and general fatigue and weakness.

Six heart failure therapies, including four drug and two nondrug treatments, have been proven to reduce deaths and are recommended by the American College of Cardiology and the American Heart Association for patients with reduced left-ventricle ejection fraction.

These treatments include:

  • ACE inhibitors or angiotensen II receptor blockers (ARBs)
  • Beta-blockers
  • Aldosterone hormone-targeting diuretics known as aldosterone antagonists
  • Hydralazine/isosorbide dinitrate
  • Cardiac resynchronization therapy (CRT), which involves the implantation of a specialized pacemaker or a combination device that also includes a defibrillator
  • Implantable cardiac defibrillator (ICD), which detects and corrects cardiac arrhythmias

Aldosterone Antagonists

Not all the treatments are appropriate for all patients, but guidelines call for them to be considered when indicated.

In their effort to explore the use of these six heart failure therapies, University of California, Los Angeles heart researcher Gregg C. Fonarow, MD, and colleagues examined clinical trials, inpatient and outpatient heart failure registries, and heart failure quality-of-life studies.

They found that out of about 2.6 million patients with reduced left-ventricular ejection fraction in the U.S., the largest number were eligible for and treated with for ACE inhibitor/ARB and beta-blocker therapy, while the smallest number were eligible for and treated with hydralazine/isosorbide dinitrate.

About 80% of eligible patients were prescribed ACE inhibitors/ARBs, and 86% were prescribed beta-blockers, but only 36% of patients eligible for aldosterone antagonists were on the drugs.

Today on WebMD

Compressed heart
Article
Salt Shockers
Slideshow
 
Inside A Heart Attack
Slideshow
lowering blood pressure
SLIDESHOW
 

Mechanical Heart
Article
Omega 3 Overview Slideshow
Slideshow
 
Atrial Fibrillation Guide
Slideshow
Simple Steps to Lower Cholesterol
Slideshow
 

Compressed heart
Article
FAQ Heart Failure
Article
 
Cholesterol Confusion
Health Check
Resolved To Quit Smoking
Slideshow
 

WebMD Special Sections