A heart transplant is surgery to replace a diseased heart in one person with a healthy one from a deceased person. Most heart transplants are done in people who have severe (end-stage) heart failure. A heart transplant may be the only treatment option if you have heart failure and other medicines and therapies have not worked. Transplantation is a complicated process. Patients must meet strict criteria to be considered for a heart transplant, and transplants are not always available when needed. Thousands of people in the United States are added to the national organ transplant waiting list each month. Follow the links below to find WebMD's comprehensive coverage about heart transplants, how they are done, when you might need one, and much more.