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    Leiomyosarcoma, Inferior Vena Cava

    Important
    It is possible that the main title of the report Leiomyosarcoma, Inferior Vena Cava is not the name you expected.

    Disorder Subdivisions

    • None

    General Discussion

    Leiomyosarcoma of the inferior vena cava is an extremely rare malignant (cancerous) tumor arising from the smooth muscle lining the walls of the large vein that carries blood from the lower body to the heart (inferior vena cava). There are essentially two types of muscles in the body - voluntary and involuntary. Smooth muscles are involuntary muscles - the brain has no conscious control over them. Smooth muscles react involuntarily in response to various stimuli. For example, the smooth muscle in walls of blood vessels contracts to help regulate blood flow.

    Leiomyosarcomas are a form of cancer. The term "cancer" refers to a group of diseases characterized by abnormal, uncontrolled cellular growth that invades surrounding tissues and may spread (metastasize) to distant bodily tissues or organs via the bloodstream, the lymphatic system, or other means. Different forms of cancer, including leiomyosarcomas, are graded according to certain histological parameters evaluated microscopically and this grade (low, intermediate, or high) gives the clinician an indication of the potential clinical aggressiveness of the tumor.

    Leiomyosarcoma is classified as a soft tissue sarcoma. Sarcomas are malignant tumors that arise from the connective tissue, which connects, supports and surrounds various structures and organs in the body. Soft tissue includes fat, muscle, nerve, tendons, tissue surrounding the joints (synovial tissue), and blood and lymph vessels. The exact cause of sarcomas including leiomyosarcomas is unknown.

    Resources

    American Cancer Society, Inc.
    250 Williams NW St
    Ste 6000
    Atlanta, GA 30303
    USA
    Tel: (404)320-3333
    Tel: (800)227-2345
    TDD: (866)228-4327
    Internet: http://www.cancer.org

    National Cancer Institute
    6116 Executive Blvd Suite 300
    Bethesda, MD 20892-8322
    USA
    Tel: (301)435-3848
    Tel: (800)422-6237
    TDD: (800)332-8615
    Email: cancergovstaff@mail.nih.gov
    Internet: http://www.cancer.gov

    OncoLink: The University of Pennsylvania Cancer Center Resource
    3400 Spruce Street
    2 Donner
    Philadelphia, PA 19104-4283
    USA
    Tel: (215)349-8895
    Fax: (215)349-5445
    Email: hampshire@uphs.upenn.edu
    Internet: http://www.oncolink.upenn.edu

    Sarcoma Foundation of America
    9899 Main Street Ste 204
    Damascus, MD 20872
    USA
    Tel: (301)253-8687
    Fax: (301)253-8690
    Email: info@curesarcoma.org
    Internet: http://www.curesarcoma.org

    Sarcoma Alliance
    775 E. Blithedale #334
    Mill Valley, CA 94941
    USA
    Tel: (415)381-7236
    Fax: (415)381-7235
    Email: info@sarcomaalliance.org
    Internet: http://www.sarcomaalliance.org

    Rare Cancer Alliance
    1649 North Pacana Way
    Green Valley, AZ 85614
    USA
    Internet: http://www.rare-cancer.org

    Northwest Sarcoma Foundation
    P.O. Box 91460
    Portland, OR 97291
    Tel: (503)954-5740
    Email: melissa@nwsarcoma.org
    Internet: http://www.nwsarcoma.org

    For a Complete Report:

    This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

    The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

    It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

    This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

    For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

    Last Updated: 8/2/2010
    Copyright 2010 National Organization for Rare Disorders, Inc.

    WebMD Medical Reference from the National Organization for Rare Disorders

    Last Updated: May 28, 2015
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

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