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Heart Disease Health Center

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New Device Jump-Starts Failing Hearts

Combo Pacemaker-Defibrillator Helps Many With Heart Failure
WebMD Health News

June 28, 2002 -- Yesterday, the FDA approved a new device that may improve the quality and length of life for more than a million people in the U.S. with heart failure.

That device, called the InSync ICD system, is, in fact, a combination of two other revolutionary devices -- a highly specialized pacemaker and a defibrillator -- both of which have proven to benefit many with this life-threatening condition.

"We think it's an important advancement in this emerging technology," says David DeLurgio, MD, director of the electrophysiology laboratory at Emory University School of Medicine in Atlanta.

He and his colleagues at Emory have been involved in studies of both devices.

Heart failure occurs when the heart's pumping action grows weaker and weaker, and needs to work harder to keep blood flowing through the body. When the heart is not pumping properly, even mild activity can cause shortness of breath or difficulty breathing.

A pacemaker device approved late last year -- called cardiac resynchronization therapy -- helps the heart's main pumping chambers fall back in step with one another. It calls for tiny electrodes to be threaded through veins into two chambers of the heart.

The InSync ICD takes that concept a step further, adding a defibrillator to the CRT system to jump-start a heart that is at risk of going into cardiac arrest.

Medtronic Inc., the maker of the device, is a WebMD sponsor.

"The original device is essentially a pacemaker that stimulates the heart continuously -- but it does not provide any protection against cardiac arrest [or sudden heart death]," DeLurgio tells WebMD.

Studies of the original InSync cardiac resynchronization therapy (CRT) have yielded encouraging long-term results. In one study reported recently, 500 patients received the device. Half the patients had the device turned on, the others didn't. After six months, all patients were switched on. The results:

  • CRT patients had worsening heart failure only half as often.
  • The risk of death or worsening heart failure dropped by 40% in the CRT group.
  • CRT patients had a 57% lower chance of worsening heart failure requiring intravenous heart medication.

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