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Heart Disease Health Center

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Clot-Busting Drugs Prevent Leg Pain, Swelling

Drugs Dissolve Dangerous Blood Clots in Legs
WebMD Health News

March 30, 2004 (Phoenix) -- Blood clots that form deep within leg veins can cause chronic swelling and leg pain when walking. A new study shows that when clot-busting drugs -- commonly used to treat heart attacks and strokes -- are given directly into the clot, they dissolve the clot and help prevent pain and swelling.

David Bloom, the NBC television correspondent who died a year ago of complications caused by these clots, called deep vein thrombosis, is arguably the best known victim of this common disorder, but thousands more suffer lifelong pain and swelling caused by deep vein thrombosis, says Patricia Thorpe, MD, a professor of interventional radiology at the University of Iowa in Iowa City.

Deep vein thrombosis, or DVT, occurs in men and women of all ages. It's also called economy class syndrome because it often afflicts travelers that spend long hours in cramped airline seats. In Bloom's case, it was caused by hours spent in a cramped military vehicle while covering the war in Iraq.

But as common as the condition is, Thorpe says that most times it is inadequately treated. Without treatment, these clots can break off and travel to other parts of the body, such as the lungs, causing pulmonary embolism (as in Bloom's case), or heart, causing heart attack. According to the Society of Interventional Radiology, one in every 100 people who develops DVT dies.

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