Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started
My Medicine

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Heart Disease Health Center

Font Size

Celebrex May Help Some Heart Patients

Study Shows the Cox-2 Drug May Help Patients With Drug-Coated Stents
WebMD Health News
Reviewed by Louise Chang, MD

Aug. 16, 2007 -- The anti-inflammatory drug Celebrex appears to improve outcomes among heart patients treated with drug-coated stents, but experts say the risk to patients may still outweigh the benefits.

In a newly reported study from South Korea, patients who took Celebrex prior to and after receiving stents to open clogged arteries were less likely to suffer another blockage in the treated vessels within six months than patients who didn't take the drug.

Reblockage due to scar tissue formation, known as restenosis, is a common complication in heart patients treated with stents.

No Increase in Heart Risk

Researchers found no evidence of an increase in heart attacks or other adverse heart events among Celebrex users, but the drug's safety in heart patients remains an open question, a spokesperson for the American Heart Association (AHA) tells WebMD.

Celebrex belongs to a class of painkillers known as Cox-2 inhibitors. The Cox-2 drug Vioxx was withdrawn from the market in the fall of 2004 after reports linked its long-term use to an increase in heart attack and stroke risk. Another Cox-2 inhibitor, Bextra, was removed from the U.S. market in 2005.

Pfizer's Celebrex is the only Cox-2 inhibitor still sold in the U.S. Early this year, AHA officials issued a statement calling for its use "only as a last resort" in heart patients.

"Celebrex has not been entirely free of adverse events in previously published trials, although its effects may not be as great as those seen with some of the other more Cox-2 selective drugs in the class," says Wake Forest University cardiology professor and AHA spokesman David Herrington, MD.

Today on WebMD

x-ray of human heart
A visual guide.
atrial fibrillation
Symptoms and causes.
heart rate graph
10 things to never do.
heart rate
Get the facts.
empty football helmet
red wine
eating blueberries
Simple Steps to Lower Cholesterol
Inside A Heart Attack
Omega 3 Sources
Salt Shockers
lowering blood pressure