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Coronary Calcium Score Color-blind?

Coronary Calcium Score May Predict Heart Disease in People of All Races
WebMD Health News

March 26, 2008 -- Heart disease is the No. 1 cause of death for U.S. men and women. The odds of being one of its victims may be made clearer by coronary calcium scores, regardless of race.

Researchers report that news in tomorrow's edition of The New England Journal of Medicine.

Before you delve into their findings, here's what you need to know about coronary arteries and coronary calcium scores (also called Agatston scores).

The coronary arteries supply oxygen-rich blood to heart muscle. In coronary artery disease, plaque builds up inside coronary arteries' walls, narrowing the arteries. Calcium is one of the components of plaque. The more plaque that is present, the more calcium is present in the walls of heart arteries. So measuring coronary calcium can be used as a surrogate for measuring plaque.

Coronary calcium measurements are derived from computed tomography (CT) scans of the heart and are quantified into "scores." Coronary calcium scores aren't new. But previous research has shown that whites have higher coronary calcium scores than minorities. That's where the new study comes in.

Coronary Calcium Scores

The researchers asked whether coronary calcium scores predicted heart "events" -- heart attack, death from coronary heart disease, or chest pain (angina) -- in whites, African-Americans, Chinese, and Hispanic adults.

The study included more than 6,700 U.S. adults with no history of heart disease.

When the study started, participants were 45-84 years old; on average, they were in their 60s. They got CT heart scans and were told whether their coronary calcium score was negative, low, average, or greater than average. They were also advised to talk to their doctor about their test results.

Participants were followed for up to five years. During that time, 17 people died of coronary heart disease, 72 had a nonfatal heart attack, and 73 had angina.

As in other studies, whites tended to have higher coronary calcium scores. But in all ethnic groups, people with higher coronary calcium scores were more likely to have heart "events" during the study.

For instance, someone with a coronary calcium score of 101-300 was more than seven times as likely to experience a heart "event" than someone with no evidence of coronary calcium.

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