Stem Cell Treatment May Relieve Angina
Study Shows Chest Pain From Heart Disease Can Be Treated With Stem Cell Therapy
Improvements in Quality of Life
Losordo says the improvements in the stem-cell-treated patients were life altering for many patients.
"To put it in human terms, patients who might have been able to sit and watch TV without symptoms could now walk at a normal pace without chest pain, and someone who could walk at a slow pace might be able to ride a bike," he says.
The study was funded by Illinois-based medical device manufacturer Baxter Healthcare, which hopes to market the machine that collects the stem cells.
A phase III study expected to involve around 50 medical centers in the U.S. is in the planning stages.
"There is an emerging notion that our bodies -- even the bodies of patients with significant disease -- contain this natural biology that can heal," Losordo says. "We are just beginning to understand and exploit this pre-installed mechanism for self-repair."
Tomaselli says the study shows that the approach is both safe and feasible in patients with significant coronary disease.
"The results are pretty undeniable," he says. "The [stem cell] treated patients had improvements in angina frequency and improvements in exertion times. The next step is to prove the treatment is clinically useful."