When plaque builds up in the coronary arteries, the heart may not get the blood that it needs to work well. This is called ischemia (say "is-KEE-mee-uh"). Ischemia can cause symptoms such as chest pain or pressure. Over time, ischemia can weaken or damage the heart. Sometimes the plaque buildup does not limit blood flow.
If the plaque breaks apart, it can cause a heart attack. A tear or rupture in the plaque tells the body to repair the injured artery lining, much as the body might heal a cut on the skin. A blood clot forms to seal the area. The blood clot can completely block blood flow to the heart muscle and cause a heart attack.
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WebMD Medical Reference from Healthwise
September 30, 2014
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