Low-Dose Aspirin Therapy - Topic Overview
Experts do not know if NSAIDs other
than ibuprofen interfere with uncoated aspirin. Also,
experts do not know if people who take a daily coated
aspirin should be concerned about ibuprofen or other NSAIDs interacting with
the aspirin. Talk to your doctor if you take these medicines every day.
How do you take low-dose aspirin?
Your doctor will recommend a dose of aspirin and how often to take it. Most people take aspirin every day to help prevent a heart attack or a stroke, but others might take aspirin every other day.
Low-dose aspirin (81 mg) is the most common dose used to prevent a heart attack or a stroke.
But the dose for daily aspirin can range from 81 mg to 325 mg. One low-dose aspirin contains 81 mg. One adult-strength aspirin contains about 325 mg.
Low-dose aspirin seems to be as effective in preventing heart
attacks and strokes as higher doses.
Take aspirin with food if it bothers your stomach.
For low-dose aspirin therapy, do not take medicines that combine aspirin with other ingredients such as
caffeine and sodium.
How does aspirin work to prevent a heart attack or stroke?
Aspirin protects you from having
a clot-related stroke in the same way it protects you from having a
Aspirin slows the blood's
clotting action by reducing the clumping of platelets. Platelets are cells that
clump together and help to form blood clots. Aspirin keeps platelets from
clumping together, thus helping to prevent or reduce blood clots.
During a heart attack, blood clots form in an already-narrowed artery and
block the flow of oxygen-rich blood to the heart muscle (or to part of the
brain, in the case of stroke). When taken during a heart attack, aspirin slows
clotting and decreases the size of the forming blood clot. Taken daily,
aspirin's anti-clotting action helps prevent a first or second heart