Blood Test Predicts Heart Attack Risk
Protein Measurement Linked to Risk for Strokes, Heart Attack, and Heart Failure
While there is some suggestion that the test could prove useful for
identifying heart risk in the general public, its most immediate use is for
patients with established heart disease.
But even among these patients, its role in disease management is not yet
clear, cardiologist Robert Bonow, MD, tells WebMD.
Bonow is chief of cardiology at Northwestern University Medical School and a
former president of the American Heart Association.
"We aren't sure at this point what to do with this information once we have
it," he says. "We can treat these patients [with elevated NT-proBNP] very
aggressively, but we should be doing that anyway."
Bonow adds that while NT-proBNP may prove to be a useful test for
asymptomatic patients with heart disease, "we don't really know this yet."
In an editorial accompanying the study, Marvin Konstam, MD, of Tufts
University School of Medicine agreed that it remains to be seen if NT-proBNP
will prove useful for the management of patients with heart disease.
Konstam tells WebMD that more study is needed to determine the value of such
"The real home run will be when we identify a marker and an intervention to
go along with it to lower risk," he says. "The best example of this is LDL, or
bad, cholesterol. We not only know that LDL
cholesterol is a predictor of heart risk, but we know that we can
lower that risk with drugs."