Skip to content
My WebMD Sign In, Sign Up

Heartburn/GERD Health Center

Font Size

Frequently Asked Questions About Heartburn and Reflux

1. When should I take an antacid vs. a Famotidine(Pepcid-AC) or Omeprazole (Prilosec)-like product?

Let's start with the basics. Antacids neutralize excess stomach acid to relieve heartburn, sour stomach, acid indigestion, and stomach upset. They are sometimes prescribed to help relieve the pain of stomach and duodenal ulcers. Some antacids also contain simethicone, an ingredient that helps eliminate excess gas.

You should take antacids exactly as directed by your doctor, or according to the manufacturer's directions. For stomach or duodenal ulcers, take the medicine for as long as your doctor tells you. If you are using the tablets, chew them well before swallowing for faster relief.

Recommended Related to Heartburn/GERD

Understanding Gastroesophageal Reflux Disease (GERD) -- Diagnosis and Treatment

Your doctor may be able to diagnose gastroesophageal reflux disease, or GERD, from your description of symptoms. The doctor may also suggest tests to rule out other possible causes of your symptoms, to monitor the degree of damage, or to determine the best treatment for you. The three main tests used when GERD is suspected or known are esophageal pH monitoring, endoscopy, and manometry. With pH monitoring, the doctor measures the amount of acid in the esophagus over a 24-48 hour period. This test...

Read the Understanding Gastroesophageal Reflux Disease (GERD) -- Diagnosis and Treatment article > >

Serious side effects can occur with an overdose or overuse of antacids. Side effects include constipation, diarrhea, change in the color of bowel movements, and stomach cramps. Products containing calcium may cause kidney stones and are more likely to cause constipation.

Products like Pepcid-AC are called histamine-2 blockers or H2 blockers. These drugs reduce production of stomach acid. Pepcid AC and other H2 blockers such as Tagamet HB, Zantac 75, and Axid AR are available in prescription-strength or in lower doses in over-the-counter varieties. These products are for relief of heartburn, acid indigestion, sour stomach, and other conditions, such as stomach ulcers.

The newest type of heartburn medication to become available without a prescription is Prilosec. Prilosec belongs to a family of drugs called proton pump inhibitors or PPIs. This type of drug is often used when antacids or H2 blockers fail. PPIs block the secretion of acid from the stomach. Prevacid and Nexium 24HR can be bought over the counter. Protonix, Aciphex, Dexilant, and Nexium are examples of other PPIs that are available only by prescription.

PPIs generally cause few side effects, but they do interact with other common drugs such as warfarin (Coumadin), some heart medications and antibiotics, so it is important to review all medications with your doctor.

Antacids work the quickest to relieve occasional heartburn. For patients who do not respond to antacids, H2 blockers and PPIs are alternatives. Remember, though, that frequent or severe episodes of reflux should always be discussed with your doctor.

Your doctor may want you to take antacids when you start taking H2 blockers to help control your symptoms until the H2 blocker takes effect. If your doctor prescribes an antacid, take it an hour before or an hour after H2 blockers. Take H2 blockers regularly for as long as directed by your doctor, even if you do not have any pain or your symptoms improve.

Possible serious side effects that need to be reported to your doctor right away include confusion, chest tightness, bleeding, sore throat, fever, irregular heartbeat, weakness, and unusual fatigue. Other less serious side effects include mild headache, dizziness, and diarrhea, which are usually temporary and will likely go away on their own.

WebMD Medical Reference

Today on WebMD

Woman eating pizza
How it starts, and how to stop it.
man with indigestion
Get lifestyle and diet tips.
 
woman shopping for heartburn relief
Medication options.
man with heartburn
Symptoms of both.
 
digestive health
Slideshow
Heartburn or Heart Attack
Article
 
heartburn
Article
Top 10 Heartburn Foods
Video
 
Is it Heartburn or Gerd
Video
digestive myths
Slideshow
 
Extreme Eats
Slideshow
graphic of esophageal area
Article