Heartburn/GERD Health Center
This article is from the WebMD News Archive
GERD, Acid Reflux Interfere With Restful Sleep
Oct. 21, 2002 -- Acid reflux during the day may hamper sleep quality at night, causing subsequent daytime sleepiness and insomnia. The long-term effects can also lead to poorer quality of life.
These findings, from two new studies presented at the 67th Annual Scientific Meeting of the American College of Gastroenterology, indicate a connection between acid reflux disease and the ability to get a good nights sleep.
In the first study, from Pennsylvania State University in Hershey, researchers found that of more than 1,500 people who had a hard time sleeping, a significant amount also complained of gastroesophageal reflux disease, also called GERD or acid reflux. They also found that people with insomnia had a high frequency of complaints of peptic ulcer disease or hiatal hernia.
"There is a significant relationship between GERD and excessive daytime sleepiness and insomnia," said Geoffrey S. Raymer, MD of the gastroenterology and hepatology department at Penn State, in a news release.
He says that more research is needed to understand the link between specific sleep disorders and specific gastrointestinal disorders.
This study was published in the July 2002 issue of the Journal of Psychosomatic Research.
The second study, from the Lynn Health Science Institute in Oklahoma City, compared data from people with GERD to data from healthy adults. Those suffering from GERD complained of heartburn at least four days a week and woke up at least one evening a week with heartburn.
The researchers also compared the sleep patterns of people with GERD and people without GERD. Although patients with GERD complained more of poor sleep quality, the study showed little difference from healthy adults, says study leader William C. Orr, PhD, and colleague in a news release. That those who did complain typically had higher levels of acid reflux during the day. -->
Important Safety Information
- KAPIDEX may not be right for everyone. You should not take KAPIDEX if you are allergic to KAPIDEX or any of its ingredients. Severe allergic reactions have been reported.
- Symptom relief does not rule out other serious stomach conditions.
- The most common side effects of KAPIDEX were diarrhea (4.8%), stomach pain (4.0%), nausea (2.9%), common cold (1.9%), vomiting (1.6%), and gas (1.6%). KAPIDEX and certain other medicines can affect each other. Before taking KAPIDEX, tell your doctor if you are taking ampicillin, atazanavir, digoxin, iron, ketoconazole, or tacrolimus. If you are taking KAPIDEX with warfarin, you may need to be monitored because serious risks could occur.
Uses of KAPIDEX
- Persistent heartburn two or more days a week, despite treatment and diet changes, could be acid reflux disease (ARD). Prescription KAPIDEX capsules are used in adults to treat heartburn related to ARD, to heal acid-related damage to the lining of the esophagus (called erosive esophagitis or EE), and to stop EE from coming back. Individual results may vary. Most damage (erosions) heals in 4–8 weeks.
Talk to your doctor or healthcare professional. Please see full Prescribing Information for KAPIDEX.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
KAPIDEX™ is a trademark of Takeda Pharmaceuticals North America, Inc., and is used under license by Takeda Pharmaceuticals America, Inc.
LPD-00767
