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Acid Blockers Linked to Pneumonia Risk

Study Shows Hospital Patients Who Take Acid-Reducing Drugs May Be at Risk for Pneumonia

Acid-Reducing Drugs and Pneumonia

There are several theories about how acid-reducing drugs might make patients more vulnerable to pneumonia.

By reducing the acid load in the stomach, the drugs may promote the growth of different bacteria in the upper gastrointestinal and upper respiratory tract linked to pneumonia.

Or they may promote pneumonia by suppressing coughing, Herzig explains. Coughing is a frequent symptom of acid reflux and it also helps clear the lungs, which reduces pneumonia risk.

Pulmonary and critical care specialist J. Randall Curtis, MD, tells WebMD that the finding are compelling but the study does not prove a link between use of proton pump inhibitors and other acid-reducing drugs and pneumonia.

Curtis is president of the American Thoracic Society and a professor in the division of pulmonary and critical care medicine at the University of Washington. "While I would argue that the study is not conclusive, I would also say that it is a wake-up call to hospital-based physicians to really look at situations in which these medications are prescribed and ask themselves if they are, in fact, indicated."

Herzig adds that the pneumonia risk to hospitalized and non-hospitalized people who have clear indications for taking acid-suppressing drugs is minimal.

"Patients who are taking these medications for symptoms such as frequent heartburn or ulcers should not stop taking them," she says. "The risk to these patients is very small."

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