Can Hepatitis C Be Cured?
The New Standard in Hepatitis C Treatment continued...
"Being able to give a treatment that is one pill a day with few side effects is very attractive," Lok says. "This is why everyone is very excited." Other new interferon-free drugs are expected to come along in the next year or two, she says.
The Viekira Pak multi-pill is prescribed for people with chronic HCV genotype 1 and works to prohibit the growth of Hep C. It’s recommended to take two ombitasvir, paritaprevir, ritonavir tablets once daily (in the morning) and one dasabuvir tablet twice daily (morning and evening) for at least 12 weeks. Viekira has a 91 – 100% cure rate.
You take simeprevir with interferon and ribavirin. The combo clears the hep C virus in up to 80% of people who take it.
Sofosbuvir can be used without interferon for people with some types of hep C. Sofosbuvir comes in an easy once-a-day pill. It takes as few as 12 weeks to work, and it cures up to 90% of people who take it. Also in November 2014, the FDA granted simeprevir (Olysio) to be used in combination with sofosbuvir (Sovaldi) without interferon or ribavirin for genotype 1 hepatitis C patients.
In 2015, ombitasvir, paritaprevir and ritonavir (Technivie) was approved for use in combination with ribavirin for treatment of genotype 4 hepatitis C infections. It is the first treatment option for genotype 4 infections that does not require interferon. It can achieve 100% cure rates. That same year, daclatasvir (Daklinza) was approved to treat genotype 3 infections. This is given with sofosbuvir (Sovaldi) with cure rates up to 98%.
That same year, daclatasvir (Daklinza) was approved to treat genotype 3 infections. This is given with sofosbuvir (Sovaldi) with cure rates up to 98%.
In 2016, approval was given for elbasvir and grazoprevir (Zepatier) to be used with or without ribavirin for treating genotype 1and 4. The single tablet drug joins Harvoni and Viekira Pak as being treatments for genotype 1 treatments that do not require interferon. Its cure rates in genotype are 94-97% while for genotype 4 it could reach 100% cure rates.