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    Experts Propose Age-Based Hepatitis C Testing

    Screening People Born From 1946 to 1970 Would Prevent Advanced Disease, Model Shows; Other Experts Want More Evidence
    WebMD Health News
    Reviewed by Louise Chang, MD

    May 9, 2011 -- Screening all people born between 1946 and 1970 for the hepatitis C virus would greatly reduce the number of people with advanced liver disease linked with the virus, according to new research.

    ''Current recommendations are to screen high-risk people," says researcher Lisa McGarry, MPH, director of health economics and outcomes research at Ingenix Life Sciences, a health information, technology, and consulting service.

    Intravenous drug users are considered at high risk.

    McGarry and her colleagues suggest that all people in the age group known as baby boomers, along with those born a few years after, be screened.

    Hepatitis C is a contagious liver disease. It ranges in severity. It can be a mild illness that lasts just a few weeks to a more serious, chronic disease that attacks the liver.

    McGarry presented her research yesterday at Digestive Disease Week in Chicago.

    The study was funded by Vertex Pharmaceuticals. The company is developing a hepatitis C drug, telaprevir.

    Otther experts who reviewed the research say the model is not enough information to suggest a change in the recommendation for hepatitis C testing.

    Hepatitis C Testing: The Disease Model

    Using a computerized model of disease progression, the researchers projected the outcomes for the age-based screening they propose.

    They chose the baby boomer population as well as those born a few years after because the hepatitis C infection rate is particularly high among them. According to the researchers, about 1.6 million people in the U.S. aged 40 to 64 are infected but do not know it.

    The virus is spread primarily through contact with the blood of an infected person, according to the CDC. Most people become infected by sharing needles or other equipment used to inject IV drugs.

    People who got a blood transfusion before 1992, when screening of the blood supply became available, are also at risk. Less often, people become infected when sharing personal care items such as toothbrushes or razors that have been in contact with an infected person's blood. Infection can occur after having sex with an infected person, but that risk is considered low. The risk becomes greater if a person has multiple sex partners, rough sex, an STD, or HIV.

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