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HIV & AIDS Health Center

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Side Effects of HIV and AIDS Drugs

Common Side Effects of HIV Drugs continued...

Protease Inhibitors (PIs) Common Side Effects Special Precautions
Agenerase (amprenavir) Nausea, diarrhea, vomiting, rash
Reyataz (atazanavir) Elevated levels of bilirubin. Nausea, headache, rash, stomach pain, vomiting, diarrhea, depression, changes in heart rhythm. Effectiveness may be reduced if also taking ritonavir and Victrelis for hepatitis C.
Prezista (darunavir) Diarrhea, nausea, headache, skin rash Effectiveness may be reduced if also taking ritonavir and Victrelis for hepatitis C.
Lexiva (fosamprenavir) Nausea, diarrhea, vomiting, rash, numbness around mouth, abdominal pain
Kaletra (lopinavir/ritonavir) Diarrhea, fatigue, headache, nausea, weakness, rash, insomnia Effectiveness may be reduced if also taking Victrelis for hepatitis C.
Viracept (nelfinavir) Diarrhea, nausea, abdominal pain, weakness, rash, anemia, joint pain
Norvir (ritonavir) Nausea, vomiting, diarrhea, taste changes, headache, dizziness, rash
Aptivus (tipranavir) Elevated liver enzymes and cholesterol levels, diarrhea, rash, nausea, vomiting, stomach pain, fatigue, headache

Fusion Inhibitor (FI) Common Side Effects Special Precautions
Fuzeon (enfuvirtide) Redness, itching, or hard lumps at injection site, insomnia, depression, diarrhea, nausea, weakness, muscle pain, loss of appetite, weight loss, flu-like symptoms

Entry Inhibitor Common Side Effects Special Precautions
Selzentry (maraviroc) Cough, stomach pain, tiredness, dizziness when standing

Integrase Inhibitors Common Side Effects Special Precautions
Isentress (raltegravir) Headache, nausea, dizziness, tiredness, insomnia

Tivicay (dolutegravir) Headaches, insomnia

Vitekta (elvitegravir) Diarrhea, nausea, headache

Severe Side Effects of HIV Drugs

WebMD Medical Reference

Reviewed by David T. Derrer, MD on February 27, 2014
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