Skip to content

    HIV & AIDS Health Center

    Font Size
    A
    A
    A

    FDA: Don't Take Amevive With HIV

    Psoriasis Drug Cuts White Blood Cells Needed by Immune System
    By
    WebMD Health News
    Reviewed by Louise Chang, MD

    Nov. 18, 2005 -- The FDA and Biogen Idec are warning HIV-positive people not to take the psoriasis drug Amevive.

    "Amevive should not be administered to patients infected with HIV," states a letter to doctors from Biogen, which makes Amevive.

    The reason is that Amevive lowers counts of CD4+ T-lymphocytes, a type of white blood cell that's part of the body's immune system.

    In HIV-positive people, lower CD4+ T-lymphocyte counts "might accelerate disease progression or increase complications of disease," states Biogen's letter.

    Amevive is a biologic drug used to treat adults with moderate to severe chronic plaque psoriasis who are candidates for phototherapy (light therapy) or systemic therapy (which affects the whole body).

    Psoriasis Psoriasis is common and often chronic (long lasting). It usually causes patches (called plaques) of itchy, scaly, and sometimes inflamed skin.

    Possible side effects from Amevive should be reported to the FDA's MedWatch program (online at www.fda.gov/medwatch or by phone at (800) FDA-1088 or (800) 332-1088) or to Biogen ((866) 263-8483).

    Today on WebMD

    misconception
    How much do you know?
    contemplative man
    What to do now.
     
    research
    Should you be tested?
    HIV under microscope
    What does it mean?
     
    HIV AIDS Screening
    Slideshow
    man opening condom wrapper
    Quiz
     
    HIV AIDS Treatment
    Feature
    Discrimination Stigma
    Feature
     
    Treatment Side Effects
    Feature
    grilled chicken and vegetables
    Article
     
    obese man standing on scale
    Article
    cold sore
    Article